Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL2868785 | 0.72 | MEN1 (0.42) | SMN1; SMN2NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL22286589 | 0.64 | SMN1; SMN2 (0.53) | L3MBTL1TP53GAASMN1; SMN2NPC1 | |
| SCHEMBL2644691 | 0.62 | NOS1 (0.41) | GAASMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL21222557 | 0.59 | TP53 (0.66) | L3MBTL1TP53GAASMN1; SMN2NPC1 | |
| Lithium Ion SCHEMBL25198385 | 0.58 | FFAR2 (0.36) | — | |
| SCHEMBL22245629 | 0.54 | — | — | |
| Acetic Acid SCHEMBL5487826 | 0.50 | CA1 (0.89) | ALDH1A1TDP1LMNA | |
| Acetic Acid SCHEMBL19714905 | 0.50 | CA1 (0.89) | ALDH1A1TDP1LMNA | |
| Acetic Acid SCHEMBL40583 | 0.50 | — | — | |
| Acetic Acid SCHEMBL28462563 | 0.50 | CA1 (0.89) | ALDH1A1TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116722143-A | Application of lithium carboxylate with N-containing six-membered ring structure and anode of anode-free lithium metal battery | 哈尔滨工业大学 | 2023-09-08 | — | — | CN | claimed |
| CN-116722143-B | Application of lithium carboxylate with N-containing six-membered ring structure and anode of anode-free lithium metal battery | 哈尔滨工业大学 | 2024-03-01 | — | — | CN | disclosed |
| CN-116722143-B | Application of lithium carboxylate with N-containing six-membered ring structure and anode of anode-free lithium metal battery | 哈尔滨工业大学 | 2024-03-01 | — | — | CN | disclosed |
| CN-116722143-A | Application of lithium carboxylate with N-containing six-membered ring structure and anode of anode-free lithium metal battery | 哈尔滨工业大学 | 2023-09-08 | — | — | CN | disclosed |
| CN-116722143-A | Application of lithium carboxylate with N-containing six-membered ring structure and anode of anode-free lithium metal battery | 哈尔滨工业大学 | 2023-09-08 | — | — | CN | disclosed |
| US-20230250060-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | NOVARTIS PHARMA AG (CH) | 2023-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230250060-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | STING1, CGAS, IRF3 | L3MBTL1 2331/4885TP53 10/4885GAA 184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.