Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CCR5 | P51681 | 1/20 | 0.45 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26187281 | 1.00 | POLB (0.47) | POLBHMOX1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL29067466 | 1.00 | POLB (0.47) | POLBHMOX1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL27177241 | 0.91 | CHRNA7 (0.49) | POLBALDH1A1CYP1A2CYP3A4GAA | |
| SCHEMBL3347314 | 0.91 | CCR5 (0.49) | POLBALDH1A1CYP1A2CYP3A4GAA | |
| SCHEMBL4186680 | 0.87 | POLB (0.41) | POLBALDH1A1CYP1A2CYP3A4GAA | |
| SCHEMBL10610746 | 0.87 | ALDH1A1 (0.44) | POLBHMOX1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL594896 | 0.86 | SRD5A1 (0.45) | SRD5A1SRD5A2EPHX2F10PRSS1 | |
| SCHEMBL594897 | 0.86 | SRD5A1 (0.45) | SRD5A1SRD5A2EPHX2F10PRSS1 | |
| SCHEMBL796858 | 0.86 | EPHX2 (0.53) | GAACYP2C9SRD5A1EPHX2 | |
| SCHEMBL2532124 | 0.86 | EPHX2 (0.53) | GAACYP2C9SRD5A1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116731029-A | Parallel ring compound and preparation and application thereof | 石药集团中奇制药技术（石家庄）有限公司 | 2023-09-12 | — | — | CN | disclosed |