Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29067537 | 0.76 | MAPT (0.41) | GAAKMT2AKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL16139265 | 0.74 | KDM4E (0.55) | GAAKMT2AKDM4EL3MBTL1LMNA | |
| SCHEMBL20508888 | 0.74 | KMT2A (0.55) | GAAKMT2AKDM4EL3MBTL1LMNA | |
| SCHEMBL29067530 | 0.73 | KMT2A (0.38) | GAAKMT2AL3MBTL1LMNAALDH1A1 | |
| SCHEMBL29067546 | 0.73 | KCNQ2 (0.38) | GAAKMT2AKDM4ELMNAALDH1A1 | |
| SCHEMBL11129968 | 0.71 | KDM4E (0.49) | GAAKMT2AKDM4EL3MBTL1LMNA | |
| SCHEMBL29067534 | 0.71 | CA12 (0.47) | GAAKMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL27685405 | 0.70 | GAA (0.61) | GAAKMT2AKDM4EL3MBTL1LMNA | |
| SCHEMBL29067526 | 0.70 | KDM4E (0.42) | GAAKMT2AKDM4EL3MBTL1LMNA | |
| SCHEMBL11521594 | 0.69 | MAPK10 (0.62) | GAAKMT2AKDM4EL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116462598-B | Allyl arylamine compound and preparation method and application thereof | 成都市第二人民医院 | 2024-08-09 | — | — | CN | disclosed |
| CN-116462598-A | Allyl arylamine compound and preparation method and application thereof | 成都市第二人民医院 | 2023-07-21 | — | — | CN | disclosed |