Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29067546 | 0.79 | KCNQ2 (0.38) | KMT2AHTTMEN1LMNARAB9A | |
| SCHEMBL29067537 | 0.79 | MAPT (0.41) | KMT2AHTTMEN1RAB9ANPC1 | |
| SCHEMBL29067509 | 0.78 | RAB9A (0.41) | KMT2AMEN1LMNARAB9ANPC1 | |
| SCHEMBL29067534 | 0.77 | CA12 (0.47) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL29067526 | 0.76 | KDM4E (0.42) | KMT2AMEN1LMNAL3MBTL1GAA | |
| SCHEMBL29067518 | 0.74 | TDP1 (0.40) | KMT2AMEN1LMNAL3MBTL1MAPT | |
| SCHEMBL29067532 | 0.73 | GAA (0.47) | KMT2AMEN1LMNANPC1L3MBTL1 | |
| SCHEMBL29067511 | 0.71 | TGM2 (0.42) | KMT2AMEN1LMNARAB9ANPC1 | |
| SCHEMBL29067520 | 0.70 | CA1 (0.47) | KMT2AHTTMEN1LMNARAB9A | |
| SCHEMBL29067507 | 0.68 | ACP1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116462598-B | Allyl arylamine compound and preparation method and application thereof | 成都市第二人民医院 | 2024-08-09 | — | — | CN | disclosed |
| CN-116462598-A | Allyl arylamine compound and preparation method and application thereof | 成都市第二人民医院 | 2023-07-21 | — | — | CN | disclosed |