Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DDX3X | O00571 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29067517 | 0.80 | KMT2A (0.44) | MAPTHTTL3MBTL1HPGDALDH1A1 | |
| SCHEMBL29067546 | 0.79 | KCNQ2 (0.38) | MAPTHTTNPC1RAB9AHPGD | |
| SCHEMBL29067530 | 0.79 | KMT2A (0.38) | MAPTHTTNPC1RAB9AL3MBTL1 | |
| SCHEMBL2228853 | 0.79 | ALDH1A1 (0.40) | MAPTHTTNPC1RAB9AHPGD | |
| SCHEMBL29067534 | 0.77 | CA12 (0.47) | MAPTNPC1RAB9AHPGDALDH1A1 | |
| SCHEMBL20206272 | 0.77 | NPC1 (0.42) | MAPTHTTNPC1RAB9AHPGD | |
| SCHEMBL29067532 | 0.76 | GAA (0.47) | MAPTNPC1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL29067526 | 0.76 | KDM4E (0.42) | L3MBTL1HPGDALDH1A1KDM4EGAA | |
| SCHEMBL20780229 | 0.74 | MAPT (0.47) | MAPTHTTNPC1RAB9AL3MBTL1 | |
| SCHEMBL29067518 | 0.74 | TDP1 (0.40) | MAPTL3MBTL1ALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116462598-B | Allyl arylamine compound and preparation method and application thereof | 成都市第二人民医院 | 2024-08-09 | — | — | CN | disclosed |
| CN-116462598-A | Allyl arylamine compound and preparation method and application thereof | 成都市第二人民医院 | 2023-07-21 | — | — | CN | disclosed |