Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Silver. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 16/20 | 0.52 |
| ▸ | CA1 | P00915 | 15/20 | 0.52 |
| ▸ | MMP1 | P03956 | 4/20 | 0.52 |
| ▸ | MMP2 | P08253 | 4/20 | 0.52 |
| ▸ | MMP9 | P14780 | 4/20 | 0.52 |
| ▸ | MMP8 | P22894 | 4/20 | 0.52 |
| ▸ | MMP13 | P45452 | 4/20 | 0.52 |
| ▸ | F2 | P00734 | 4/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Silver SCHEMBL2920139 | 0.97 | CA2 (0.54) | CA2CA1MMP1MMP2MMP9 | |
| Silver SCHEMBL28693681 | 0.97 | CA2 (0.54) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL1831160 | 0.94 | CA2 (0.52) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL544823 | 0.94 | CA2 (0.52) | CA2CA1MMP1MMP2MMP9 | |
| Lithium Ion SCHEMBL443931 | 0.94 | CA2 (0.52) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL1835423 | 0.94 | CA2 (0.52) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL1496640 | 0.94 | CA2 (0.52) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL5960728 | 0.94 | CA2 (0.52) | CA2CA1MMP1MMP2MMP9 | |
| Lithium Ion SCHEMBL21802717 | 0.94 | CA2 (0.52) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL20583880 | 0.94 | CA2 (0.52) | CA2CA1MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11821868-B2 | Detection and analysis of olefins in petroleum by electrospray ionization mass spectrometry | ExxonMobil Technology and Engineering Company (US) | 2023-11-21 | — | — | US | claimed |
| CN-114249635-A | Novel chiral (R) -binaphthol titanium complex and preparation method and application thereof | 山西医科大学 | 2022-03-29 | — | — | CN | claimed |
| CN-110437100-B | Preparation method and application of novel ionic salicylaldehyde Schiff base zirconium complex | 山西医科大学 | 2022-03-11 | — | — | CN | claimed |
| US-20210302371-A1 | DETECTION AND ANALYSIS OF OLEFINS IN PETROLEUM BY ELECTROSPRAY IONIZATION MASS SPECTROMETRY | EXXONMOBIL RES & ENG CO (US) | 2021-09-30 | — | — | US | claimed |
| US-11821868-B2 | Detection and analysis of olefins in petroleum by electrospray ionization mass spectrometry | ExxonMobil Technology and Engineering Company (US) | 2023-11-21 | — | — | US | disclosed |
| CN-114249635-A | Novel chiral (R) -binaphthol titanium complex and preparation method and application thereof | 山西医科大学 | 2022-03-29 | — | — | CN | disclosed |
| CN-110437100-B | Preparation method and application of novel ionic salicylaldehyde Schiff base zirconium complex | 山西医科大学 | 2022-03-11 | — | — | CN | disclosed |
| CN-110483563-B | Preparation method and application of novel ionic beta-naphthoic aldehyde Schiff base zirconium complex | 山西医科大学 | 2021-12-28 | — | — | CN | disclosed |
| US-20210302371-A1 | DETECTION AND ANALYSIS OF OLEFINS IN PETROLEUM BY ELECTROSPRAY IONIZATION MASS SPECTROMETRY | EXXONMOBIL RES & ENG CO (US) | 2021-09-30 | — | — | US | disclosed |
| CN-107790186-B | Novel decamethyl cyclopentadienyl zirconium complex and preparation method and application thereof | 山西医科大学 | 2020-10-30 | — | — | CN | disclosed |
| CN-107722049-B | Preparation and application of novel ionic binuclear Schiff base titanium complex | 山西医科大学 | 2020-06-30 | — | — | CN | disclosed |
| EP-1154321-B1 | Chemical amplification type positive resist compositions and sulfonium salts | SUMITOMO CHEMICAL CO (JP) | 2010-08-25 | — | — | EP | disclosed |
| EP-1207423-A1 | Chemically amplifying type positive resist composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-05-22 | — | — | EP | disclosed |
| US-6358665-B1 | ONIUM SALT PRECURSOR FOR GENERATING FLUOROALKYLSULFONATE | CLARIANT INTERNATIONAL LTD. (CH) | 2002-03-19 | — | — | US | disclosed |
| US-20020006582-A1 | Chemical amplification type positive resist compositions and sulfonium salts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-01-17 | — | — | US | disclosed |
| EP-1154321-A1 | Chemical amplification type positive resist compositions and sulfonium salts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-11-14 | — | — | EP | disclosed |
| EP-1033624-A1 | RADIATION-SENSITIVE COMPOSITION OF CHEMICAL AMPLIFICATION TYPE | Clariant International Ltd. (CH) | 2000-09-06 | — | — | EP | disclosed |
| US-5985888-A | Camptothecin compounds with combined topoisomarase I inhibition and DNA alkylation properties | RESEARCH TRIANGLE INSTITUTE (US) | 1999-11-16 | — | — | US | disclosed |
| US-5932588-A | Camptothecin compounds with combined topoisomerase I inhibition and DNA alkylation properties | RESEARCH TRIANGLE INSTITUTE (US) | 1999-08-03 | — | — | US | disclosed |
| WO-1997019085-A1 | CAMPTOTHECIN COMPOUNDS WITH COMBINED TOPOISOMERASE I INHIBITION AND DNA ALKYLATION PROPERTIES | RESEARCH TRIANGLE INSTITUTE (US) | 1997-05-29 | — | — | WO | disclosed |