Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Silver. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 14/20 | 0.54 |
| ▸ | CA1 | P00915 | 13/20 | 0.54 |
| ▸ | MMP1 | P03956 | 3/20 | 0.54 |
| ▸ | MMP2 | P08253 | 3/20 | 0.54 |
| ▸ | MMP9 | P14780 | 3/20 | 0.54 |
| ▸ | MMP8 | P22894 | 3/20 | 0.54 |
| ▸ | MMP13 | P45452 | 3/20 | 0.54 |
| ▸ | F2 | P00734 | 4/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Silver SCHEMBL28693681 | 1.00 | CA2 (0.54) | CA2CA1MMP1MMP2MMP9 | |
| Silver SCHEMBL2906769 | 0.97 | CA2 (0.52) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL1496679 | 0.95 | CA2 (0.54) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL18917616 | 0.95 | CA2 (0.54) | CA2CA1MMP1MMP2MMP9 | |
| Potassium Ion SCHEMBL544675 | 0.95 | CA2 (0.54) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL6915441 | 0.95 | CA2 (0.54) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL6913561 | 0.95 | CA2 (0.54) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL6914831 | 0.95 | CA2 (0.54) | CA2CA1MMP1MMP2MMP9 | |
| Potassium Ion SCHEMBL4443223 | 0.95 | CA2 (0.54) | CA2CA1MMP1MMP2MMP9 | |
| Lithium Ion SCHEMBL18008092 | 0.95 | CA2 (0.54) | CA2CA1MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110437100-B | Preparation method and application of novel ionic salicylaldehyde Schiff base zirconium complex | 山西医科大学 | 2022-03-11 | — | — | CN | claimed |
| US-4788125-A | CATIONICALLY DEPOLYMERIZABLE POLYMER AND PHOTOINITIATOR; LASER SCANNING | THE MEAD CORPORATION (US) | 1988-11-29 | — | — | US | claimed |
| CN-114249635-A | Novel chiral (R) -binaphthol titanium complex and preparation method and application thereof | 山西医科大学 | 2022-03-29 | — | — | CN | disclosed |
| CN-110437100-B | Preparation method and application of novel ionic salicylaldehyde Schiff base zirconium complex | 山西医科大学 | 2022-03-11 | — | — | CN | disclosed |
| CN-107790186-B | Novel decamethyl cyclopentadienyl zirconium complex and preparation method and application thereof | 山西医科大学 | 2020-10-30 | — | — | CN | disclosed |
| CN-107722049-B | Preparation and application of novel ionic binuclear Schiff base titanium complex | 山西医科大学 | 2020-06-30 | — | — | CN | disclosed |
| CN-104529725-A | Method for synthesizing ketone through catalyzing and hydrolyzing alkyne with silver perfluorooctanesulfonate | UNIV HUNAN | 2015-04-22 | — | — | CN | disclosed |
| CN-104529725-A | Method for synthesizing ketone through catalyzing and hydrolyzing alkyne with silver perfluorooctanesulfonate | UNIV HUNAN | 2015-04-22 | — | — | CN | disclosed |
| EP-1154321-B1 | Chemical amplification type positive resist compositions and sulfonium salts | SUMITOMO CHEMICAL CO (JP) | 2010-08-25 | — | — | EP | disclosed |
| EP-1020767-B1 | Chemical amplification type positive resist composition | SUMITOMO CHEMICAL CO (JP) | 2006-12-06 | — | — | EP | disclosed |
| CN-1220914-C | Chemical reinforcing photoresist structure composition and sulfonium salt | SUMITOMO CHEMICAL CO (JP) | 2005-09-28 | — | — | CN | disclosed |
| US-20020081523-A1 | Chemical amplification type positive resist composition | SUMITOMO CHEMICAL CO., LTD. | 2002-06-27 | — | — | US | disclosed |
| US-6406830-B2 | BIS(SULFONIUM METHYL)KETONE BISPERFLUOROALKANESULFONATE ACID GENERATOR WITH TRIPHENYLSULFONIUM OR DIPHENYLIODONIUM SALTS, AND A RESIN HAVING A UNIT UNSTABLE TO AN ACID, SUCH AS 2-ALKYL-2-ADAMANTYL (METH)ACRYLATE; RESOLUTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-06-18 | — | — | US | disclosed |
| US-6383713-B1 | ADAMANTYL ACRYLATE POLYMERS AND ACID GENERATORS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-05-07 | — | — | US | disclosed |
| US-20020006582-A1 | Chemical amplification type positive resist compositions and sulfonium salts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-01-17 | — | — | US | disclosed |
| CN-1322968-A | Chemical reinforcing photoresist structure composition and sulfonium salt | SUMITOMO CHEMICAL CO (JP) | 2001-11-21 | — | — | CN | disclosed |
| EP-1154321-A1 | Chemical amplification type positive resist compositions and sulfonium salts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-11-14 | — | — | EP | disclosed |
| EP-1020767-A1 | Chemical amplification type positive resist composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-07-19 | — | — | EP | disclosed |
| EP-0295344-A1 | Imaging material and an image-forming process | THE MEAD CORPORATION (US) | 1988-12-21 | — | — | EP | disclosed |
| US-4788125-A | CATIONICALLY DEPOLYMERIZABLE POLYMER AND PHOTOINITIATOR; LASER SCANNING | THE MEAD CORPORATION (US) | 1988-11-29 | — | — | US | disclosed |