Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23857686 | 0.85 | PDE4A (0.41) | POLBKMT2ATSHRCYP1A2SMN1; SMN2 | |
| SCHEMBL20821077 | 0.80 | IRAK4 (0.33) | TDP1 | |
| SCHEMBL2257497 | 0.80 | KMT2A (0.41) | POLBKMT2ATSHRCYP2D6CYP1A2 | |
| SCHEMBL18084131 | 0.80 | IRAK4 (0.34) | — | |
| SCHEMBL27313851 | 0.77 | KMT2A (0.40) | POLBKMT2ACYP2D6CYP1A2SMN1; SMN2 | |
| SCHEMBL4400125 | 0.76 | POLB (0.45) | POLBKMT2ATSHRCYP2D6CYP1A2 | |
| SCHEMBL16119357 | 0.76 | SLC6A1 (0.32) | — | |
| SCHEMBL8972820 | 0.75 | ALDH1A1 (0.42) | TSHRSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL3745667 | 0.75 | CYP1A2 (0.44) | POLBKMT2ATSHRCYP2D6CYP1A2 | |
| SCHEMBL16233030 | 0.75 | IRAK4 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116669727-A | Triazole-pyridinyl substituted azacyclohexylacetic acid compounds as LPA receptor antagonists | 唯久生物有限公司 | 2023-08-29 | — | — | CN | disclosed |