Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 6/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.59 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.59 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.59 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2032476 | 0.97 | ESR1 (0.62) | ESR1ESR2PDCD1CD274ADRB2 | |
| SCHEMBL633374 | 0.97 | ESR1 (0.62) | ESR1ESR2PDCD1CD274ADRB2 | |
| SCHEMBL2037513 | 0.97 | ESR1 (0.62) | ESR1ESR2PDCD1CD274ADRB2 | |
| Bromide SCHEMBL23672238 | 0.95 | ESR1 (0.59) | ESR1ESR2PDCD1CD274ADRB2 | |
| Hydrochloric Acid SCHEMBL3178913 | 0.95 | ESR1 (0.59) | ESR1ESR2PDCD1CD274ADRB2 | |
| Bromide SCHEMBL15901678 | 0.95 | ESR1 (0.59) | ESR1ESR2PDCD1CD274ADRB2 | |
| Bromide SCHEMBL4909882 | 0.95 | ESR1 (0.59) | ESR1ESR2PDCD1CD274ADRB2 | |
| Hydrochloric Acid SCHEMBL14830851 | 0.95 | ESR1 (0.59) | ESR1ESR2PDCD1CD274ADRB2 | |
| Hydrochloric Acid SCHEMBL8702706 | 0.95 | ESR1 (0.59) | ESR1ESR2PDCD1CD274ADRB2 | |
| SCHEMBL18664397 | 0.90 | ESR1 (0.54) | ESR1ESR2PDCD1CD274ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115440893-B | Tin-lead perovskite solar cell based on 4-hydroxyphenylethyl ammonium halide modified layer and preparation method thereof | 武汉大学 | 2024-03-26 | — | — | CN | disclosed |
| CN-115440893-A | Tin-lead perovskite solar cell based on 4-hydroxyphenylethyl ammonium halide salt modification layer and preparation method thereof | 武汉大学 | 2022-12-06 | — | — | CN | disclosed |