Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.54 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.54 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20497350 | 1.00 | ESR1 (0.54) | ESR1ESR2PDCD1CD274ADRB2 | |
| SCHEMBL18664389 | 1.00 | ESR1 (0.54) | ESR1ESR2PDCD1CD274ADRB2 | |
| SCHEMBL633374 | 0.93 | ESR1 (0.62) | ESR1ESR2PDCD1CD274ADRB2 | |
| SCHEMBL2032476 | 0.93 | ESR1 (0.62) | ESR1ESR2PDCD1CD274ADRB2 | |
| SCHEMBL2037513 | 0.93 | ESR1 (0.62) | ESR1ESR2PDCD1CD274ADRB2 | |
| Bromide SCHEMBL23672238 | 0.90 | ESR1 (0.59) | ESR1ESR2PDCD1CD274ADRB2 | |
| Hydrochloric Acid SCHEMBL14830851 | 0.90 | ESR1 (0.59) | ESR1ESR2PDCD1CD274ADRB2 | |
| Hydrochloric Acid SCHEMBL8702706 | 0.90 | ESR1 (0.59) | ESR1ESR2PDCD1CD274ADRB2 | |
| Bromide SCHEMBL4909882 | 0.90 | ESR1 (0.59) | ESR1ESR2PDCD1CD274ADRB2 | |
| Iodide SCHEMBL29068279 | 0.90 | ESR1 (0.59) | ESR1ESR2PDCD1CD274ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118108676-A | Benzenesulfonamide compound, pharmaceutical composition and application thereof | 中国药科大学 | 2024-05-31 | — | — | CN | disclosed |
| EP-3349581-B1 | HEPATITIS B CORE PROTEIN MODULATORS | ASSEMBLY BIOSCIENCES INC (US) | 2021-12-01 | — | — | EP | disclosed |
| CN-108347942-B | Hepatitis B core protein modulators | 组装生物科学股份有限公司 | 2021-09-03 | — | — | CN | disclosed |
| US-10766890-B2 | Hepatitis B core protein modulators | ASSEMBLY BIOSCIENCES, INC. (US) | 2020-09-08 | — | — | US | disclosed |
| US-20180265484-A1 | HEPATITIS B CORE PROTEIN MODULATORS | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION | 2018-09-20 | — | — | US | disclosed |
| CN-108347942-A | HEPATITIS B CORE PROTEIN MODULATORS | 组装生物科学股份有限公司 | 2018-07-31 | — | — | CN | disclosed |
| WO-2017048962-A1 | HEPATITIS B CORE PROTEIN MODULATORS | ASSEMBLY BIOSCIENCES, INC. (US) | 2017-03-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180265484-A1 | HEPATITIS B CORE PROTEIN MODULATORS | HAVCR2, FABP1, MAVS | ESR1 2250/4885ESR2 1652/4885PDCD1 1438/4885 |
| US-10766890-B2 | Hepatitis B core protein modulators | HAVCR2, FABP1, MAVS | ESR1 2250/4885ESR2 1652/4885PDCD1 1438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.