Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | STS | P08842 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL826363 | 0.84 | PDE4B (0.56) | PDE4BMAPTTP53STSKDM4E | |
| SCHEMBL21381706 | 0.84 | PDE4B (0.56) | PDE4BMAPTTP53STSKDM4E | |
| SCHEMBL23211834 | 0.82 | LIPE (0.46) | PDE4BMAPTTP53STSKDM4E | |
| SCHEMBL21381778 | 0.82 | LIPE (0.46) | PDE4BMAPTTP53STSKDM4E | |
| SCHEMBL19701837 | 0.78 | ADAM17 (0.53) | PDE4BMAPTSTSKDM4ETHRB | |
| SCHEMBL12279418 | 0.76 | TP53 (0.60) | PDE4BMAPTTP53STSKDM4E | |
| SCHEMBL15534541 | 0.76 | PDE4B (0.54) | PDE4BMAPTTP53STSKDM4E | |
| SCHEMBL22988918 | 0.75 | PDE4B (0.58) | PDE4BMAPTTP53STSLMNA | |
| SCHEMBL12279642 | 0.75 | PDE4B (0.58) | PDE4BMAPTTP53STSLMNA | |
| SCHEMBL28298497 | 0.75 | PDE4B (0.56) | PDE4BMAPTKDM4ETHRBDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111936503-B | Oxazine monoacylglycerol lipase (MAGL) inhibitors | 豪夫迈·罗氏有限公司 | 2023-09-12 | — | — | CN | disclosed |