Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23212046 | 0.85 | MMP13 (0.53) | GPR119MMP13DPP4MEN1KMT2A | |
| SCHEMBL31668220 | 0.84 | DPP4 (0.53) | GPR119MMP13DPP4MEN1KMT2A | |
| SCHEMBL23211714 | 0.83 | MMP13 (0.48) | GPR119MMP13DPP4MEN1KMT2A | |
| SCHEMBL23211854 | 0.83 | MMP13 (0.51) | GPR119MMP13DPP4MEN1KMT2A | |
| SCHEMBL5705714 | 0.83 | MMP13 (0.56) | GPR119MMP13DPP4MEN1KMT2A | |
| SCHEMBL29068347 | 0.82 | MMP13 (0.50) | GPR119MMP13DPP4MEN1KMT2A | |
| SCHEMBL23212019 | 0.81 | MMP13 (0.49) | GPR119MMP13DPP4MEN1KMT2A | |
| SCHEMBL5940502 | 0.81 | MMP13 (0.52) | GPR119MMP13DPP4MEN1KMT2A | |
| SCHEMBL5705674 | 0.81 | MMP13 (0.49) | GPR119MMP13DPP4MEN1KMT2A | |
| SCHEMBL21384665 | 0.80 | MMP13 (0.48) | GPR119MMP13DPP4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111936503-B | Oxazine monoacylglycerol lipase (MAGL) inhibitors | 豪夫迈·罗氏有限公司 | 2023-09-12 | — | — | CN | disclosed |