Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29068343 | 0.89 | HDAC1 (0.41) | MMP13MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL7417677 | 0.86 | MMP13 (0.53) | MMP13MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL4380300 | 0.85 | MMP13 (0.53) | MMP13MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL29068375 | 0.83 | CACNA1B (0.41) | DPP4 | |
| SCHEMBL23211893 | 0.83 | MMP13 (0.49) | MMP13MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL21384762 | 0.83 | MMP13 (0.49) | MMP13MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL29068361 | 0.82 | GPR119 (0.48) | MMP13MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL4393991 | 0.81 | MMP13 (0.55) | MMP13MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL5934111 | 0.80 | MMP13 (0.60) | MMP13MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL25326881 | 0.79 | MMP13 (0.53) | MMP13MEN1KMT2ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111936503-B | Oxazine monoacylglycerol lipase (MAGL) inhibitors | 豪夫迈·罗氏有限公司 | 2023-09-12 | — | — | CN | disclosed |