SCHEMBL29068461

SCHEMBL29068461

CCN(c1ccc2c(c1)-c1ccc(NCc3ccccc3)cc1C2)c1ccc(C)cc1C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.40
MAOA P21397 2/20 0.37
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
HSD17B3 P37058 1/20 0.34
DHFR P00374 1/20 0.34
MAOB P27338 1/20 0.34
RXRA P19793 2/20 0.33
RXRB P28702 2/20 0.33
RXRG P48443 2/20 0.33
NOS2 P35228 1/20 0.33
MAPT P10636 3/20 0.33
HPGD P15428 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
HSD17B10 Q99714 1/20 0.33
ITK Q08881 1/20 0.32
FFAR1 O14842 1/20 0.32
FFAR4 Q5NUL3 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30572819 1.00 HTT (0.40) HTTMAOANPC1RAB9AMEN1
SCHEMBL29068519 0.89 HTT (0.47) HTTMAOANPC1RAB9AMEN1
SCHEMBL29068521 0.88 HTT (0.41) HTTMAOANPC1RAB9AMEN1
SCHEMBL30572813 0.88 HTT (0.41) HTTMAOANPC1RAB9AMEN1
SCHEMBL29068523 0.88 RAB9A (0.34) MAOANPC1RAB9AMEN1KMT2A
SCHEMBL7868915 0.81 CNR2 (0.45) HTTMAOANPC1RAB9AMEN1
SCHEMBL29068489 0.80 HTT (0.49) HTTMAOANPC1RAB9AMEN1
SCHEMBL29068464 0.79 NR3C2 (0.37) HTTMAOANPC1RAB9AMEN1
SCHEMBL27633770 0.75 HPGD (0.42) MAOANPC1RAB9AMEN1KMT2A
SCHEMBL29068525 0.73 RXRA (0.40) RXRARXRBRXRGMAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116745115-A Laminate, card and case 索尼集团公司 2023-09-12 CN disclosed