Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ITK | Q08881 | 1/20 | 0.42 |
| ▸ | ACP1 | P24666 | 1/20 | 0.42 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.42 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.42 |
| ▸ | SSU72 | Q9NP77 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22556768 | 0.78 | MRGPRX4 (0.53) | RORCPOLBMAPTMEN1KMT2A | |
| SCHEMBL22556736 | 0.72 | THRA (0.48) | POLBALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL29391574 | 0.72 | THRA (0.48) | POLBALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL22570643 | 0.72 | THRA (0.48) | POLBMAPTMEN1KMT2AHPGD | |
| Hydrochloric Acid SCHEMBL29392777 | 0.72 | THRA (0.47) | POLBMAPTMEN1KMT2AHPGD | |
| Hydrochloric Acid SCHEMBL22556835 | 0.72 | THRA (0.47) | POLBMAPTMEN1KMT2AHPGD | |
| SCHEMBL22556779 | 0.70 | THRA (0.43) | MAPTHPGDLMNAMAPK1L3MBTL1 | |
| SCHEMBL20225812 | 0.70 | L3MBTL1 (0.54) | HTTPOLBALDH1A1MAPTMEN1 | |
| SCHEMBL15075274 | 0.69 | MAPT (0.56) | POLBALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL11812683 | 0.69 | MAPT (0.76) | RORCHTTALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116745289-A | Agonists of free fatty acid receptor 1 and their use in diseases associated with said receptor | 奥洛治疗有限公司 | 2023-09-12 | — | — | CN | disclosed |