Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.35 |
| ▸ | FLT3 | P36888 | 2/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
| ▸ | CCND1 | P24385 | 1/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CCND3 | P30281 | 1/20 | 0.31 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29698954 | 0.73 | RXFP1 (0.43) | RXFP1NTRK1HSD11B1ARKDM4E | |
| SCHEMBL29083570 | 0.73 | RXFP1 (0.43) | RXFP1NTRK1HSD11B1ARKDM4E | |
| SCHEMBL25593890 | 0.71 | HTR6 (0.50) | — | |
| SCHEMBL14648923 | 0.69 | RXFP1 (0.59) | RXFP1NTRK1MAPTKDM4EALDH1A1 | |
| SCHEMBL30549107 | 0.67 | RXFP1 (0.37) | RXFP1ARKDM4EALDH1A1TDP1 | |
| SCHEMBL29699020 | 0.66 | CDK7 (0.42) | RXFP1CCNE1CDK2 | |
| SCHEMBL21178205 | 0.66 | CDK7 (0.42) | RXFP1CCNE1CDK2 | |
| SCHEMBL21178911 | 0.64 | RXFP1 (0.35) | RXFP1 | |
| SCHEMBL21178218 | 0.64 | RXFP1 (0.36) | RXFP1 | |
| SCHEMBL21178209 | 0.63 | RXFP1 (0.34) | RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116745277-A | Aromatic heterocyclic compound, pharmaceutical composition and application thereof | 湃隆生物科技有限公司（香港） | 2023-09-12 | — | — | CN | disclosed |