Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | MDM4 | O15151 | 2/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.34 |
| ▸ | TUBB | P07437 | 2/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29698954 | 1.00 | RXFP1 (0.43) | RXFP1NPY5RPKMNTRK1MDM4 | |
| SCHEMBL29698972 | 0.84 | NPY5R (0.40) | NPY5RPKMTP53HPGDHTR6 | |
| SCHEMBL29174619 | 0.84 | PKM (0.40) | NPY5RPKMHTR6GRM4HSD11B1 | |
| SCHEMBL14648923 | 0.77 | RXFP1 (0.59) | RXFP1NTRK1TP53THRBKDM4E | |
| SCHEMBL25593890 | 0.76 | HTR6 (0.50) | HTR6 | |
| SCHEMBL29068549 | 0.73 | RXFP1 (0.39) | RXFP1NTRK1HPGDHSD11B1AR | |
| SCHEMBL30549107 | 0.71 | RXFP1 (0.37) | RXFP1HPGDARKDM4EALDH1A1 | |
| SCHEMBL29699020 | 0.71 | CDK7 (0.42) | RXFP1HTR6 | |
| SCHEMBL21178205 | 0.71 | CDK7 (0.42) | RXFP1HTR6 | |
| SCHEMBL29699098 | 0.70 | GRM4 (0.35) | NPY5RPKMMDM4MDM2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116670123-A | Aromatic heterocyclic compound, pharmaceutical composition and application thereof | 湃隆生物科技有限公司（香港） | 2023-08-29 | — | — | CN | disclosed |