Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 10/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
| ▸ | LSS | P48449 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL29068649 | 1.00 | DNM1 (0.50) | DNM1ALDH1A1TP53CYP3A4ALOX15 | |
| Bromide SCHEMBL11042968 | 1.00 | DNM1 (0.50) | DNM1ALDH1A1TP53CYP3A4ALOX15 | |
| Hydrochloric Acid SCHEMBL19331394 | 0.96 | DNM1 (0.50) | DNM1HSP90AA1RAD52HTTSLC22A1 | |
| Hydrochloric Acid SCHEMBL27626657 | 0.96 | DNM1 (0.50) | DNM1HSP90AA1RAD52HTTSLC22A1 | |
| Hydrochloric Acid SCHEMBL29068569 | 0.96 | DNM1 (0.50) | DNM1HSP90AA1RAD52HTTSLC22A1 | |
| Iodide SCHEMBL19549305 | 0.96 | DNM1 (0.50) | DNM1HSP90AA1RAD52HTTSLC22A1 | |
| Water SCHEMBL29182137 | 0.96 | APAF1 (0.48) | DNM1HSP90AA1RAD52HTTSLC22A1 | |
| Hydrochloric Acid SCHEMBL29068599 | 0.96 | DNM1 (0.50) | DNM1HSP90AA1RAD52HTTSLC22A1 | |
| SCHEMBL1325838 | 0.96 | DNM1 (0.44) | DNM1HSP90AA1RAD52HTTSLC22A1 | |
| Acetic Acid SCHEMBL29078335 | 0.85 | LSS (0.39) | DNM1HTTLSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116559150-A | Luminescent substrate enhancer, preparation method thereof and kit | 深圳市天大生物医疗器械有限公司 | 2023-08-08 | — | — | CN | claimed |
| CN-116559150-A | Luminescent substrate enhancer, preparation method thereof and kit | 深圳市天大生物医疗器械有限公司 | 2023-08-08 | — | — | CN | disclosed |