Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 8/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 3/20 | 0.43 |
| ▸ | CES1 | P23141 | 3/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10320692 | 1.00 | HSP90AA1 (0.52) | HSP90AA1FAAHMEN1KMT2AMAPK1 | |
| Hydrochloric Acid SCHEMBL4943874 | 1.00 | HSP90AA1 (0.52) | HSP90AA1FAAHMEN1KMT2AMAPK1 | |
| Hydrochloric Acid SCHEMBL731708 | 1.00 | HSP90AA1 (0.52) | HSP90AA1FAAHMEN1KMT2AMAPK1 | |
| Hydrochloric Acid SCHEMBL29068608 | 1.00 | HSP90AA1 (0.52) | HSP90AA1FAAHMEN1KMT2AMAPK1 | |
| Hydrochloric Acid SCHEMBL29286438 | 1.00 | HSP90AA1 (0.52) | HSP90AA1FAAHMEN1KMT2AMAPK1 | |
| Hydrochloric Acid SCHEMBL1194814 | 0.98 | HSP90AA1 (0.50) | HSP90AA1FAAHMEN1KMT2AMAPK1 | |
| SCHEMBL74417 | 0.98 | HSP90AA1 (0.53) | HSP90AA1FAAHMEN1KMT2AMAPK1 | |
| SCHEMBL680383 | 0.98 | HSP90AA1 (0.53) | HSP90AA1FAAHMEN1KMT2AMAPK1 | |
| SCHEMBL9409008 | 0.98 | HSP90AA1 (0.53) | HSP90AA1FAAHMEN1KMT2AMAPK1 | |
| SCHEMBL10420923 | 0.98 | HSP90AA1 (0.53) | HSP90AA1FAAHMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116559150-A | Luminescent substrate enhancer, preparation method thereof and kit | 深圳市天大生物医疗器械有限公司 | 2023-08-08 | — | — | CN | disclosed |