Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 8/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 3/20 | 0.43 |
| ▸ | CES1 | P23141 | 3/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10320692 | 1.00 | HSP90AA1 (0.52) | HSP90AA1FAAHMEN1KMT2AMAPK1 | |
| Hydrochloric Acid SCHEMBL4943874 | 1.00 | HSP90AA1 (0.52) | HSP90AA1FAAHMEN1KMT2AMAPK1 | |
| Hydrochloric Acid SCHEMBL29068608 | 1.00 | HSP90AA1 (0.52) | HSP90AA1FAAHMEN1KMT2AMAPK1 | |
| Hydrochloric Acid SCHEMBL29286438 | 1.00 | HSP90AA1 (0.52) | HSP90AA1FAAHMEN1KMT2AMAPK1 | |
| Hydrochloric Acid SCHEMBL29068584 | 1.00 | HSP90AA1 (0.52) | HSP90AA1FAAHMEN1KMT2AMAPK1 | |
| Hydrochloric Acid SCHEMBL1194814 | 0.98 | HSP90AA1 (0.50) | HSP90AA1FAAHMEN1KMT2AMAPK1 | |
| SCHEMBL74417 | 0.98 | HSP90AA1 (0.53) | HSP90AA1FAAHMEN1KMT2AMAPK1 | |
| SCHEMBL680383 | 0.98 | HSP90AA1 (0.53) | HSP90AA1FAAHMEN1KMT2AMAPK1 | |
| SCHEMBL9409008 | 0.98 | HSP90AA1 (0.53) | HSP90AA1FAAHMEN1KMT2AMAPK1 | |
| SCHEMBL10420923 | 0.98 | HSP90AA1 (0.53) | HSP90AA1FAAHMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021134463-A1 | COMPOSITION FOR CONDITIONING KERATIN MATERIALS | L'OREAL (FR) | 2021-07-08 | — | — | WO | claimed |
| US-9271918-B2 | Colouring composition | KAO GERMANY GMBH (DE) | 2016-03-01 | — | — | US | claimed |
| EP-4206236-A1 | COMPOUNDS, THEIR SYNTHESIS AND COMPOSITIONS COMPRISING THE COMPOUNDS FOR ENHANCED DEPOSITION OF POLYMERS ONTO HAIR SURFACES | Kao Corporation (JP) | 2023-07-05 | — | — | EP | disclosed |
| EP-1949885-B2 | Aerosol hair styling composition comprising natural starch | KAO GERMANY GMBH (DE) | 2021-07-21 | — | — | EP | disclosed |
| EP-2736479-B1 | POST-FOAMING GEL COMPOSITION | KAO GERMANY GMBH (DE) | 2019-10-16 | — | — | EP | disclosed |
| EP-2658507-B1 | OXIDATIVE COLOURING COMPOSITION | KAO GERMANY GMBH (DE) | 2019-04-24 | — | — | EP | disclosed |
| EP-2346483-B1 | Composition and process for treating hair | KAO GERMANY GMBH (DE) | 2019-04-03 | — | — | EP | disclosed |
| EP-3237547-B1 | DIRECT DYES AND COMPOSITION COMPRISING THE DYES | KAO GERMANY GMBH (DE) | 2019-03-20 | — | — | EP | disclosed |
| US-10196520-B2 | Direct dyes and composition comprising the dyes | KAO GERMANY GMBH (DE) | 2019-02-05 | — | — | US | disclosed |
| EP-2025328-B1 | Hair styling composition | KAO GERMANY GMBH (DE) | 2018-10-24 | — | — | EP | disclosed |
| EP-1927346-B1 | Hair styling emulsion composition | KAO GERMANY GMBH (DE) | 2018-10-03 | — | — | EP | disclosed |
| US-20080124293-A1 | COMPOSITION FOR KERATIN FIBRES | KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) | 2008-05-29 | — | — | US | disclosed |
| US-20080120791-A1 | Colouring Composition | KPSS-KAO PROFESSIONAL SALON SERVICE GMBH (DE) | 2008-05-29 | — | — | US | disclosed |
| EP-1925284-A1 | Conditioning composition for keratin fibres | KPSS-Kao Professional Salon Services GmbH (DE) | 2008-05-28 | — | — | EP | disclosed |
| EP-1925285-A1 | Conditioner composition for keratin fibres | KPSS-Kao Professional Salon Services GmbH (DE) | 2008-05-28 | — | — | EP | disclosed |
| EP-1925283-A1 | Conditioning composition for keratin fibres | KPSS-Kao Professional Salon Services GmbH (DE) | 2008-05-28 | — | — | EP | disclosed |
| EP-1925287-A1 | Colouring composition | KPSS Kao Professional Salon Services GmbH (DE) | 2008-05-28 | — | — | EP | disclosed |
| US-20080118456-A1 | Styling Emulsion Composition | KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) | 2008-05-22 | — | — | US | disclosed |
| EP-1923043-A1 | Anti-dandruff conditioner composition | KPSS-Kao Professional Salon Services GmbH (DE) | 2008-05-21 | — | — | EP | disclosed |
| EP-1923046-A1 | Hair styling emulsion composition | KPSS-Kao Professional Salon Services GmbH (DE) | 2008-05-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080124293-A1 | COMPOSITION FOR KERATIN FIBRES | KRT18, MICA, CUTA | HSP90AA1 1972/4885FAAH 4845/4885MEN1 571/4885 |
| US-20080118456-A1 | Styling Emulsion Composition | KRT18, SUCLG1, POLR1C | HSP90AA1 3144/4885FAAH 619/4885MEN1 2245/4885 |
| US-10196520-B2 | Direct dyes and composition comprising the dyes | KRT18, TUBB4A, BRDT | HSP90AA1 1839/4885FAAH 2920/4885MEN1 4120/4885 |
| US-20080120791-A1 | Colouring Composition | KRT18, MICA, HLA-C | HSP90AA1 2272/4885FAAH 4734/4885MEN1 1101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.