Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 9/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
| ▸ | MAP4K1 | Q92918 | 6/20 | 0.35 |
| ▸ | PGR | P06401 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25340605 | 0.81 | NR3C1 (0.42) | FFAR4NR3C1CYP11B1CYP11B2MAP4K1 | |
| SCHEMBL695279 | 0.79 | NR3C1 (0.39) | NR3C1CYP11B1CYP11B2PGR | |
| SCHEMBL29509715 | 0.78 | NR3C1 (0.46) | FFAR4NR3C1CYP11B1CYP11B2PGR | |
| SCHEMBL25338683 | 0.78 | NR3C1 (0.46) | FFAR4NR3C1CYP11B1CYP11B2PGR | |
| SCHEMBL695356 | 0.72 | NR3C1 (0.51) | NR3C1CYP11B2PGR | |
| SCHEMBL20764751 | 0.72 | CYP11B1 (0.36) | CYP11B1CYP11B2MAP4K1MAPK1 | |
| SCHEMBL20764749 | 0.71 | SMO (0.45) | NR3C1CYP11B1CYP11B2 | |
| SCHEMBL694709 | 0.71 | CYP11B2 (0.48) | NR3C1CYP11B1CYP11B2PGR | |
| SCHEMBL29509857 | 0.70 | NR3C1 (0.53) | NR3C1PGR | |
| SCHEMBL25338509 | 0.70 | NR3C1 (0.53) | NR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116744918-A | HSD17B13 inhibitors and uses thereof | FL2022-001公司 | 2023-09-12 | — | — | CN | disclosed |