Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 1/20 | 0.35 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.32 |
| ▸ | HTR3B | O95264 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.32 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30572960 | 1.00 | EPAS1 (0.35) | EPAS1TMPRSS4HTR3EHTR3BHTR3A | |
| SCHEMBL26523664 | 0.82 | KIF11 (0.33) | CA1CA2CA4CA6KIF11 | |
| SCHEMBL29490992 | 0.82 | KIF11 (0.33) | CA1CA2CA4CA6KIF11 | |
| SCHEMBL31302117 | 0.77 | NOTUM (0.33) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL26120541 | 0.72 | TAS2R14 (0.34) | EPAS1TMPRSS4NOTUM | |
| SCHEMBL4768740 | 0.70 | NOTUM (0.32) | NOTUM | |
| SCHEMBL15948212 | 0.69 | EPAS1 (0.44) | EPAS1NOTUM | |
| SCHEMBL3838860 | 0.69 | KIF11 (0.37) | TMPRSS4KIF11NOTUM | |
| SCHEMBL31507812 | 0.69 | KIF11 (0.37) | TMPRSS4KIF11NOTUM | |
| SCHEMBL31302156 | 0.69 | HSD17B10 (0.36) | CA1CA2CA4CA6AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116744918-A | HSD17B13 inhibitors and uses thereof | FL2022-001公司 | 2023-09-12 | — | — | CN | disclosed |