Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | PYGL | P06737 | 1/20 | 0.33 |
| ▸ | PYGM | P11217 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2909513 | 0.85 | HRH4 (0.33) | HRH4PYGLPYGM | |
| SCHEMBL1278047 | 0.78 | HRH4 (0.36) | HRH4PYGLPYGMPIK3CG | |
| SCHEMBL1278044 | 0.78 | HRH4 (0.36) | HRH4PYGLPYGMPIK3CG | |
| SCHEMBL1277687 | 0.76 | KDM4E (0.38) | HRH4PYGLPYGM | |
| SCHEMBL1277688 | 0.76 | KDM4E (0.38) | HRH4PYGLPYGM | |
| SCHEMBL1653191 | 0.75 | LMNA (0.36) | HRH4PYGLPYGM | |
| SCHEMBL3029211 | 0.74 | BRD4 (0.41) | PIK3CDPIK3CG | |
| SCHEMBL15005634 | 0.72 | POLB (0.33) | — | |
| SCHEMBL15005631 | 0.72 | POLB (0.33) | — | |
| SCHEMBL1655841 | 0.67 | HRH4 (0.35) | HRH4PYGLPYGM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2220081-A2 | GLUCOKINASE ACTIVATORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE INGREDIENT | LG Life Sciences Ltd. (KR) | 2010-08-25 | — | — | EP | disclosed |
| WO-2009082152-A2 | GLUCOKINASE ACTIVATORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE INGREDIENT | LG LIFE SCIENCES LTD. (KR) | 2009-07-02 | — | — | WO | disclosed |