Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | POLA1 | P09884 | 1/20 | 0.42 |
| ▸ | POLG | P54098 | 1/20 | 0.42 |
| ▸ | FAP | Q12884 | 1/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lb80380 SCHEMBL4270816 | 0.95 | FAP (0.46) | ABCB11POLA1POLGFAPSLC22A6 | |
| Lb80380 SCHEMBL29355183 | 0.95 | FAP (0.46) | ABCB11POLA1POLGFAPSLC22A6 | |
| SCHEMBL13178775 | 0.90 | ABCB11 (0.41) | ABCB11POLA1POLGFAPSLC22A6 | |
| SCHEMBL2914228 | 0.90 | ABCB11 (0.42) | ABCB11POLA1POLGFAPSLC22A6 | |
| SCHEMBL2913853 | 0.89 | ABCB11 (0.40) | ABCB11POLA1POLGFAPSLC22A6 | |
| SCHEMBL2914790 | 0.88 | KDM4E (0.39) | ABCB11POLA1POLGFAPSLC22A6 | |
| SCHEMBL2905699 | 0.88 | FAP (0.45) | ABCB11POLA1POLGFAPSLC22A6 | |
| SCHEMBL2912371 | 0.88 | FAP (0.45) | ABCB11POLA1POLGFAPSLC22A6 | |
| SCHEMBL2913623 | 0.88 | FAP (0.49) | ABCB11POLA1POLGFAPSLC22A6 | |
| SCHEMBL2912291 | 0.87 | ABCB11 (0.42) | ABCB11POLA1POLGFAPSLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358198-B1 | NOVEL ACYCLIC NUCLEOSIDE PHOSPHONATE DERIVATIVES, SALTS THEREOF AND PROCESS FOR THE PREPARATION OF THE SAME | LG LIFE SCIENCES LTD (KR) | 2010-08-25 | — | — | EP | claimed |
| US-7157448-B2 | Acyclic nucleoside phosphonate derivatives, salts thereof and process for the preparation of the same | LG LIFE SCIENCES LTD. (KR) | 2007-01-02 | — | — | US | claimed |
| EP-1358198-B1 | NOVEL ACYCLIC NUCLEOSIDE PHOSPHONATE DERIVATIVES, SALTS THEREOF AND PROCESS FOR THE PREPARATION OF THE SAME | LG LIFE SCIENCES LTD (KR) | 2010-08-25 | — | — | EP | disclosed |