Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 13/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 10/20 | 0.42 |
| ▸ | PDE4A | P27815 | 10/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.42 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2909443 | 0.90 | PDE4D (0.43) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL2906904 | 0.77 | GPR119 (0.41) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL2908927 | 0.77 | GPR119 (0.41) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL2909446 | 0.69 | PDE4D (0.45) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL7357750 | 0.67 | LMNA (0.68) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL2908176 | 0.66 | EGFR (0.38) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL22491593 | 0.66 | GPR119 (0.51) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL22773259 | 0.66 | GPR119 (0.51) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL6529700 | 0.65 | PDE4D (0.45) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL6469431 | 0.65 | PDE4D (0.46) | PDE4DPDE4BPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1692109-B1 | PHOSPHODIESTERASE 4 INHIBITORS, INCLUDING N-SUBSTITUTED DIARYLAMINE ANALOGS | MEMORY PHARM CORP (US) | 2010-08-18 | — | — | EP | claimed |