Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.34 |
| ▸ | PPARG | P37231 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | MME | P08473 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL506238 | 0.73 | LMNA (0.37) | EPHX1 | |
| SCHEMBL3748652 | 0.73 | TRPA1 (0.40) | MMEEPHX1 | |
| SCHEMBL2075972 | 0.72 | EPHX1 (0.35) | EPHX1 | |
| SCHEMBL4869728 | 0.72 | EPHX1 (0.44) | KMT2AEPHX1 | |
| SCHEMBL300073 | 0.72 | EPHX1 (0.35) | KMT2AEPHX1 | |
| SCHEMBL1462830 | 0.72 | CYP1A2 (0.44) | PPARAPPARGMMEEPHX1 | |
| SCHEMBL1155558 | 0.70 | TRPA1 (0.38) | EPHX1 | |
| SCHEMBL406396 | 0.70 | MIF (0.39) | KMT2AEPHX1 | |
| SCHEMBL938718 | 0.70 | EPHX1 (0.37) | EPHX1 | |
| SCHEMBL5818025 | 0.70 | ADORA2A (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2152080-A1 | NOVEL SOLUBLE 1,4 BENZODIAZEPINE COMPOUNDS AND STABLE SALTS THEREOF | The Regents of the University of Michigan (US) | 2010-02-17 | — | — | EP | disclosed |
| WO-2008133635-A1 | NOVEL SOLUBLE 1,4 BENZODIAZEPINE COMPOUNDS AND STABLE SALTS THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2008-11-06 | — | — | WO | disclosed |