Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | ERN1 | O75460 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | COMT | P21964 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | METAP2 | P50579 | 1/20 | 0.48 |
| ▸ | METAP1 | P53582 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL113967 | 1.00 | MAPT (0.58) | MAPTKDM4EERN1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28278818 | 0.98 | MAPT (0.56) | MAPTKDM4EERN1MEN1KMT2A | |
| SCHEMBL27503543 | 0.98 | MAPT (0.56) | MAPTKDM4EERN1MEN1KMT2A | |
| Bromide SCHEMBL28322003 | 0.98 | MAPT (0.56) | MAPTKDM4EERN1MEN1KMT2A | |
| Phenol SCHEMBL27859532 | 0.90 | KDM4E (0.48) | MAPTKDM4EERN1MEN1KMT2A | |
| Quinoline SCHEMBL27726526 | 0.90 | ALDH1A1 (0.63) | MAPTKDM4EERN1MEN1KMT2A | |
| SCHEMBL128549 | 0.84 | NCF1 (0.56) | MAPTKDM4EERN1MEN1KMT2A | |
| Oxyquinoline SCHEMBL22115717 | 0.83 | TSHR (0.66) | MAPTKDM4EMEN1KMT2ATSHR | |
| SCHEMBL27752837 | 0.82 | CA12 (0.49) | MAPTKDM4EERN1MEN1KMT2A | |
| 1-Naphthol SCHEMBL27401651 | 0.82 | ALDH1A1 (0.63) | MAPTKDM4EERN1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4458916-A1 | PHOTOCATALYTICALLY ACTIVE COATING COMPOSITION, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF | TriOptoTec GmbH (DE) | 2024-11-06 | — | — | EP | disclosed |
| EP-4441203-A1 | METHODS AND COMPOSITIONS RELATED TO ENGINEERED CANNABINOID RECEPTORS | Board of Regents, The University of Texas System (US) | 2024-10-09 | — | — | EP | disclosed |
| CN-111073974-B | Genetic markers for predicting responsiveness to treatment | 豪夫迈·罗氏有限公司 | 2024-04-09 | — | — | CN | disclosed |
| WO-2023102541-A1 | METHODS AND COMPOSITIONS RELATED TO ENGINEERED CANNABINOID RECEPTORS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-06-08 | — | — | WO | disclosed |
| CN-101516852-B | Quinoline derivatives with 5-ht-binding properties | HOFFMANN LA ROCHE | 2011-11-16 | — | — | CN | disclosed |
| US-7825253-B2 | 2-aminoquinoline derivatives | HOFFMANN-LA ROCHE INC. (US) | 2010-11-02 | — | — | US | disclosed |
| EP-2076495-B1 | QUINOLINE DERIVATIVES WITH 5-HT-BINDING PROPERTIES | HOFFMANN LA ROCHE (CH) | 2010-08-18 | — | — | EP | disclosed |
| CN-101516852-A | Quinoline derivatives with 5-HT-binding properties | HOFFMANN LA ROCHE (CH) | 2009-08-26 | — | — | CN | disclosed |