Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYNJ2 | O15056 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.53 |
| ▸ | CA12 | O43570 | 3/20 | 0.53 |
| ▸ | CA1 | P00915 | 3/20 | 0.53 |
| ▸ | CA2 | P00918 | 3/20 | 0.53 |
| ▸ | CA7 | P43166 | 3/20 | 0.53 |
| ▸ | CA9 | Q16790 | 3/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA6 | P23280 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | FASN | P49327 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30487686 | 0.84 | SYNJ2 (0.46) | SYNJ2PTGS2CA12CA1CA2 | |
| Maclurin SCHEMBL29523046 | 0.84 | SYNJ2 (0.69) | SYNJ2PTGS2CA12CA1CA2 | |
| Maclurin SCHEMBL758337 | 0.84 | SYNJ2 (0.69) | SYNJ2PTGS2CA12CA1CA2 | |
| SCHEMBL724972 | 0.77 | KDM4E (0.59) | SYNJ2PTGS2CA12CA1CA2 | |
| SCHEMBL27183192 | 0.77 | CDC25B (0.70) | PTGS2CA12CA1CA2CA7 | |
| SCHEMBL30872965 | 0.77 | CDC25B (0.70) | PTGS2CA12CA1CA2CA7 | |
| SCHEMBL7717195 | 0.77 | CA12 (0.55) | SYNJ2PTGS2CA12CA1CA2 | |
| SCHEMBL2127547 | 0.76 | CYP3A4 (0.59) | PTGS2CA12CA1CA2CA7 | |
| SCHEMBL29419953 | 0.76 | CYP3A4 (0.59) | PTGS2CA12CA1CA2CA7 | |
| SCHEMBL29450505 | 0.75 | MEN1 (0.65) | SYNJ2PTGS2CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116539901-A | Application of differential metabolite as diagnostic marker and kit | 中国医学科学院北京协和医院 | 2023-08-04 | — | — | CN | disclosed |