Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | STAT1 | P42224 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19348115 | 0.85 | ALDH1A1 (0.36) | RAB9ANPC1MAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL18959819 | 0.73 | RAB9A (0.39) | RAB9ANPC1MAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL18959775 | 0.71 | KMT2A (0.46) | RAB9ANPC1MAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL18907373 | 0.70 | ALDH1A1 (0.35) | RAB9ANPC1MAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL14945379 | 0.68 | ACACB (0.32) | ALDH1A1POLBKMT2AHPGDMEN1 | |
| SCHEMBL6256079 | 0.67 | MEN1 (0.51) | RAB9AMAPK1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL14945336 | 0.67 | ACACB (0.34) | ALDH1A1MAPT | |
| SCHEMBL14945530 | 0.67 | GRIN2D (0.35) | SMN1; SMN2ALDH1A1POLBMAPTKMT2A | |
| SCHEMBL19361562 | 0.67 | ALDH1A1 (0.38) | ALDH1A1MAPT | |
| SCHEMBL7030156 | 0.66 | ACACB (0.58) | SMN1; SMN2MAPTKMT2AADORA2BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116745299-A | Thienopyrimidine derivatives | 正大天晴药业集团股份有限公司 | 2023-09-12 | — | — | CN | disclosed |