Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.64 |
| ▸ | CA2 | P00918 | 1/20 | 0.64 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.64 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.64 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.64 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29072091 | 1.00 | CA1 (0.64) | CA1CA2SIRT2SIRT1SIRT3 | |
| SCHEMBL29326176 | 0.96 | CA1 (0.60) | CA1CA2SIRT2SIRT1SIRT3 | |
| SCHEMBL29072085 | 0.91 | FOLH1 (0.76) | SIRT2SIRT1FOLH1HTTMMP2 | |
| SCHEMBL29072081 | 0.91 | FOLH1 (0.76) | SIRT2SIRT1FOLH1HTTMMP2 | |
| SCHEMBL18348898 | 0.91 | SIRT2 (0.72) | CA1CA2SIRT2SIRT1SIRT3 | |
| SCHEMBL15976615 | 0.90 | CA1 (0.66) | CA1CA2SIRT2SIRT1SIRT3 | |
| SCHEMBL29072115 | 0.89 | KLK7 (0.60) | CA1CA2FOLH1HTT | |
| SCHEMBL29072109 | 0.89 | KLK7 (0.60) | CA1CA2FOLH1HTT | |
| SCHEMBL15253875 | 0.89 | KLK7 (0.60) | CA1CA2SIRT2SIRT1SIRT3 | |
| SCHEMBL30823356 | 0.89 | CA1 (0.60) | CA1CA2SIRT2SIRT1SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116744944-A | Low-immunogenicity biotherapeutic medicine | 奥斯普瑞生物制药有限公司 | 2023-09-12 | — | — | CN | disclosed |