SCHEMBL29072091

SCHEMBL29072091

COC(=O)[C@H](CCCCNC(=O)OCc1ccccc1)NC(=O)CCCNC(=O)OCc1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.64
CA2 P00918 1/20 0.64
SIRT2 Q8IXJ6 2/20 0.64
SIRT1 Q96EB6 2/20 0.64
SIRT3 Q9NTG7 1/20 0.64
FOLH1 Q04609 4/20 0.63
HTT P42858 1/20 0.60
MMP2 P08253 1/20 0.54
MMP9 P14780 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29072142 1.00 CA1 (0.64) CA1CA2SIRT2SIRT1SIRT3
SCHEMBL29326176 0.96 CA1 (0.60) CA1CA2SIRT2SIRT1SIRT3
SCHEMBL29072085 0.91 FOLH1 (0.76) SIRT2SIRT1FOLH1HTTMMP2
SCHEMBL29072081 0.91 FOLH1 (0.76) SIRT2SIRT1FOLH1HTTMMP2
SCHEMBL18348898 0.91 SIRT2 (0.72) CA1CA2SIRT2SIRT1SIRT3
SCHEMBL15976615 0.90 CA1 (0.66) CA1CA2SIRT2SIRT1SIRT3
SCHEMBL29072115 0.89 KLK7 (0.60) CA1CA2FOLH1HTT
SCHEMBL29072109 0.89 KLK7 (0.60) CA1CA2FOLH1HTT
SCHEMBL15253875 0.89 KLK7 (0.60) CA1CA2SIRT2SIRT1SIRT3
SCHEMBL30823356 0.89 CA1 (0.60) CA1CA2SIRT2SIRT1SIRT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4651901-A1 CYCLING LYSOSOMAL TARGETING ANTIBODY CONJUGATES Lycia Therapeutics, Inc. (US) 2025-11-26 EP disclosed
WO-2025035040-A1 LYSOSOMAL TARGETING BIFUNCTIONAL MOLECULES FOR DEGRADATION OF MUSCLE-SPECIFIC KINASE AUTOANTIBODIES LYCIA THERAPEUTICS, INC. (US) 2025-02-13 WO disclosed
US-20240238422-A1 Hypoimmunogenic Biotherapeutics ADAXION THERAPEUTICS, INC. 2024-07-18 US disclosed
EP-4274582-A1 HYPOIMMUNOGENIC BIOTHERAPEUTICS Osprey Biopharmaceuticals, Inc. (US) 2023-11-15 EP disclosed
CN-116744944-A Low-immunogenicity biotherapeutic medicine 奥斯普瑞生物制药有限公司 2023-09-12 CN disclosed
WO-2022150726-A1 HYPOIMMUNOGENIC BIOTHERAPEUTICS OSPREY BIOPHARMACEUTICALS, INC. (US) 2022-07-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240238422-A1 Hypoimmunogenic Biotherapeutics FCGR3B, CD47, IL2 CA1 4539/4885CA2 4456/4885SIRT2 3910/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.