Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 6/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | GMNN | O75496 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20490754 | 1.00 | MAPK1 (0.53) | MAPK1MAPTLMNATSHRGMNN | |
| SCHEMBL20490776 | 1.00 | MAPK1 (0.53) | MAPK1MAPTLMNATSHRGMNN | |
| SCHEMBL20490781 | 1.00 | MAPK1 (0.53) | MAPK1MAPTLMNATSHRGMNN | |
| SCHEMBL27166420 | 1.00 | MAPK1 (0.53) | MAPK1MAPTLMNATSHRGMNN | |
| SCHEMBL27166469 | 1.00 | MAPK1 (0.53) | MAPK1MAPTLMNATSHRGMNN | |
| SCHEMBL29959266 | 1.00 | MAPK1 (0.53) | MAPK1MAPTLMNATSHRGMNN | |
| SCHEMBL15028239 | 0.94 | KDM4A (0.44) | MAPK1MAPTLMNATSHRGMNN | |
| SCHEMBL15027342 | 0.94 | KDM4A (0.44) | MAPK1MAPTLMNATSHRGMNN | |
| SCHEMBL517835 | 0.94 | KDM4A (0.44) | MAPK1MAPTLMNATSHRGMNN | |
| SCHEMBL20490773 | 0.94 | KDM4A (0.44) | MAPK1MAPTLMNATSHRGMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025080945-A1 | LIPID NANOPARTICLES | CodeBridgeBio Inc. (US) | 2025-04-17 | — | — | WO | claimed |
| US-20260115138-A1 | LIPID NANOPARTICLES | CODEBRIDGEBIO INC (US) | 2026-04-30 | — | — | US | disclosed |
| US-12427111-B2 | Lipid nanoparticles | CodeBridgeBio Inc. (US) | 2025-09-30 | — | — | US | disclosed |
| WO-2025080945-A1 | LIPID NANOPARTICLES | CodeBridgeBio Inc. (US) | 2025-04-17 | — | — | WO | disclosed |
| US-20250120914-A1 | LIPID NANOPARTICLES | CodeBridgeBio Inc. | 2025-04-17 | — | — | US | disclosed |
| CN-116763756-A | Lipid nanoparticle and preparation method and application thereof | 中国科学院化学研究所 | 2023-09-19 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260115138-A1 | LIPID NANOPARTICLES | LDLR, CETP, PLIN3 | MAPK1 1548/4885MAPT 1578/4885LMNA 200/4885 |
| US-20250120914-A1 | LIPID NANOPARTICLES | PNLIP, PLIN3, LIPG | MAPK1 3195/4885MAPT 2390/4885LMNA 978/4885 |
| US-12427111-B2 | Lipid nanoparticles | PNLIP, PLIN3, LIPG | MAPK1 3195/4885MAPT 2390/4885LMNA 978/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.