Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 4/20 | 0.46 |
| ▸ | MAP4K1 | Q92918 | 4/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 2/20 | 0.39 |
| ▸ | GAK | O14976 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29073083 | 0.90 | NR3C1 (0.44) | NR3C1MAP4K1CYP11B1CYP11B2GRM5 | |
| SCHEMBL29073113 | 0.81 | SLC2A1 (0.39) | NR3C1MAP4K1HPGDSALDH1A1GAA | |
| SCHEMBL25367846 | 0.79 | NR3C1 (0.54) | NR3C1MAP4K1CYP11B1CYP11B2MAPT | |
| SCHEMBL29073108 | 0.78 | SLC2A1 (0.37) | NR3C1CYP11B1CYP11B2HPGDSALDH1A1 | |
| SCHEMBL30749528 | 0.75 | CYP11B1 (0.38) | MAP4K1CYP11B1CYP11B2ALDH1A1L3MBTL1 | |
| SCHEMBL27170578 | 0.75 | CYP11B1 (0.38) | MAP4K1CYP11B1CYP11B2ALDH1A1L3MBTL1 | |
| SCHEMBL29073127 | 0.74 | MAP4K1 (0.37) | NR3C1MAP4K1HPGDSALDH1A1GAA | |
| SCHEMBL29073098 | 0.74 | NR3C1 (0.49) | NR3C1CYP11B1CYP11B2 | |
| SCHEMBL25368535 | 0.74 | MAP4K1 (0.51) | NR3C1MAP4K1CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL25366652 | 0.73 | NR3C1 (0.47) | NR3C1MAP4K1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116600801-A | HSD17B13 inhibitors and uses thereof | FL2022-001公司 | 2023-08-15 | — | — | CN | disclosed |