Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | MAP4K1 | Q92918 | 8/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | BRD1 | O95696 | 1/20 | 0.33 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.33 |
| ▸ | BRPF3 | Q9ULD4 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27170578 | 1.00 | CYP11B1 (0.38) | CYP11B1CYP11B2MAP4K1IRAK4ALDH1A1 | |
| SCHEMBL27170740 | 0.82 | MAP4K1 (0.47) | CYP11B1CYP11B2MAP4K1ALDH1A1LMNA | |
| SCHEMBL30749607 | 0.82 | MAP4K1 (0.47) | CYP11B1CYP11B2MAP4K1ALDH1A1LMNA | |
| SCHEMBL27170629 | 0.79 | MAP4K1 (0.43) | MAP4K1IRAK4 | |
| SCHEMBL30749658 | 0.79 | MAP4K1 (0.43) | MAP4K1IRAK4 | |
| SCHEMBL30749615 | 0.77 | ACLY (0.36) | CYP11B1CYP11B2MAP4K1IRAK4ALDH1A1 | |
| SCHEMBL27170791 | 0.77 | ACLY (0.36) | CYP11B1CYP11B2MAP4K1IRAK4ALDH1A1 | |
| SCHEMBL29073115 | 0.75 | NR3C1 (0.46) | CYP11B1CYP11B2MAP4K1ALDH1A1L3MBTL1 | |
| SCHEMBL30749628 | 0.74 | MAP4K1 (0.45) | CYP11B1CYP11B2MAP4K1ALDH1A1L3MBTL1 | |
| SCHEMBL27170710 | 0.74 | MAP4K1 (0.45) | CYP11B1CYP11B2MAP4K1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240083853-A1 | HSD17B13 INHIBITORS AND USES THEREOF | FL2022-001, INC. | 2024-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240083853-A1 | HSD17B13 INHIBITORS AND USES THEREOF | HSD17B3, HSD17B11, HSD17B1 | CYP11B1 16/4885CYP11B2 19/4885MAP4K1 3312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.