SCHEMBL29073368

SCHEMBL29073368

NC(=O)OC1Cc2nc(Br)ccc2NC1=O

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
XIAP P98170 1/20 0.31
BIRC2 Q13490 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29073364 0.77 GSK3B (0.38)
SCHEMBL29073339 0.75 BRD4 (0.40)
SCHEMBL29073331 0.72 ALDH1A1 (0.33)
SCHEMBL25330289 0.72 PYGL (0.36)
SCHEMBL29073421 0.72 BRD4 (0.44)
SCHEMBL29073318 0.70 GSK3B (0.32)
SCHEMBL30767983 0.69 GAA (0.44)
SCHEMBL28704831 0.69 ALDH1A1 (0.40)
SCHEMBL28704834 0.69 ALDH1A1 (0.40)
SCHEMBL2782193 0.68 MEN1 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116783165-A 1,2,3, 4-tetrahydroquinoline derivatives as YAP/TAZ-TEAD activation inhibitors for the treatment of cancer 天主教鲁汶大学 2023-09-19 CN disclosed