Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | TTK | P33981 | 2/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.40 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.40 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.40 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28054249 | 0.74 | ALDH1A1 (0.59) | ALDH1A1CYP2D6ATMPOLB | |
| SCHEMBL16784440 | 0.74 | MET (0.47) | CSF1RMETAURKBKDRCCNA2 | |
| SCHEMBL23045757 | 0.73 | ALDH1A1 (0.58) | CSF1RALDH1A1CYP2D6ATMNTRK1 | |
| SCHEMBL22736088 | 0.72 | AURKA (0.52) | AURKBKDRMTORAURKAINCENP | |
| SCHEMBL16784439 | 0.72 | MET (0.53) | CSF1RCYP2D6METCCNA2CDK2 | |
| Ammonia Solution, Strong SCHEMBL25279198 | 0.72 | ALDH1A1 (0.56) | CSF1RALDH1A1CYP2D6ATMNTRK1 | |
| SCHEMBL13810669 | 0.69 | CLK1 (0.48) | CSF1RMETNTRK1NTRK3NTRK2 | |
| SCHEMBL5990507 | 0.69 | CLK1 (0.51) | METAURKBKDRCCNA2CDK2 | |
| Hydrochloric Acid SCHEMBL7522555 | 0.68 | ALDH1A1 (0.68) | ALDH1A1CYP2D6ATMPOLB | |
| SCHEMBL29999550 | 0.68 | ALDH1A1 (0.54) | ALDH1A1CYP2D6ATMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116554151-A | Kinesin KIF18A inhibitor and application thereof | 上海湃隆生物科技有限公司 | 2023-08-08 | — | — | CN | disclosed |