Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBOAT4 | Q96T53 | 6/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 2/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | NOS2 | P35228 | 2/20 | 0.35 |
| ▸ | FFAR2 | O15552 | 5/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 4/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30527887 | 1.00 | MBOAT4 (0.49) | MBOAT4PIK3CAMTORNOS3NOS1 | |
| SCHEMBL26151136 | 0.83 | PIK3CA (0.41) | MBOAT4PIK3CAMTORNOS3NOS1 | |
| SCHEMBL30788625 | 0.82 | IDH1 (0.41) | MBOAT4PIK3CAMTORNOS3NOS1 | |
| SCHEMBL26883498 | 0.82 | IDH1 (0.41) | MBOAT4PIK3CAMTORNOS3NOS1 | |
| SCHEMBL22122604 | 0.81 | PIK3CA (0.42) | MBOAT4PIK3CAMTORNOS3NOS1 | |
| SCHEMBL26151845 | 0.78 | FFAR2 (0.38) | PIK3CAMTORFFAR2 | |
| SCHEMBL26151146 | 0.77 | WHR1 (0.45) | MBOAT4PIK3CAMTORNOS3NOS1 | |
| SCHEMBL22122552 | 0.77 | MBOAT4 (0.44) | MBOAT4PIK3CAMTORNOS3NOS1 | |
| SCHEMBL29074131 | 0.76 | PIK3CA (0.39) | MBOAT4PIK3CAMTORNOS3NOS1 | |
| SCHEMBL29074141 | 0.75 | FFAR2 (0.41) | PIK3CAMTORNOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116554151-B | Kinesin KIF18A inhibitor and application thereof | 上海湃隆生物科技有限公司 | 2024-09-20 | — | — | CN | disclosed |
| CN-116554151-A | Kinesin KIF18A inhibitor and application thereof | 上海湃隆生物科技有限公司 | 2023-08-08 | — | — | CN | disclosed |