Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 4/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | MGAM | O43451 | 2/20 | 0.43 |
| ▸ | SI | P14410 | 2/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21430990 | 1.00 | JAK2 (0.48) | JAK2NR4A2CREBBPKDM4EALDH1A1 | |
| SCHEMBL18418508 | 0.87 | JAK2 (0.50) | JAK2KDM4EALDH1A1GAAMGAM | |
| SCHEMBL21430930 | 0.87 | NTRK1 (0.48) | JAK2NR4A2KDM4EALDH1A1MAPT | |
| SCHEMBL30159234 | 0.87 | MGAM (0.47) | JAK2NR4A2CREBBPGAAMGAM | |
| SCHEMBL21430994 | 0.87 | MGAM (0.47) | JAK2NR4A2CREBBPGAAMGAM | |
| SCHEMBL21431020 | 0.85 | NR4A2 (0.43) | JAK2NR4A2CREBBPKDM4EALDH1A1 | |
| SCHEMBL22890848 | 0.85 | MGAM (0.41) | JAK2NR4A2CREBBPGAAMGAM | |
| SCHEMBL21430993 | 0.84 | JAK2 (0.50) | JAK2NR4A2CREBBPKDM4EALDH1A1 | |
| SCHEMBL22890549 | 0.82 | ALDH1A1 (0.39) | JAK2NR4A2CREBBPKDM4EALDH1A1 | |
| SCHEMBL21431002 | 0.78 | ALDH1A1 (0.44) | JAK2KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11566018-B2 | Treatment of infectious disease | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2023-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11566018-B2 | Treatment of infectious disease | INMT, MAVS, EIF2AK2 | JAK2 193/4885NR4A2 3791/4885CREBBP 3180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.