Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.60 |
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | NSUN3 | Q9H649 | 1/20 | 0.59 |
| ▸ | CASP3 | P42574 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.59 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.59 |
| ▸ | KDM4A | O75164 | 1/20 | 0.58 |
| ▸ | KDM4B | O94953 | 1/20 | 0.58 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | GCK | P35557 | 1/20 | 0.56 |
| ▸ | GRM5 | P41594 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12258301 | 0.90 | NPC1 (0.71) | NPC1RAB9ACASP3KMT2ASENP8 | |
| SCHEMBL29074200 | 0.84 | ADORA3 (0.67) | KMT2AADORA3KDM4AKDM4BKDM5B | |
| SCHEMBL29074224 | 0.83 | PDE5A (0.61) | NPC1RAB9ANSUN3KMT2AADORA3 | |
| SCHEMBL29074233 | 0.83 | ADORA3 (0.66) | NPC1RAB9AKMT2AADORA3KDM4A | |
| SCHEMBL18997288 | 0.83 | ADORA3 (0.82) | NPC1RAB9AKMT2AADORA3KDM4A | |
| SCHEMBL1796559 | 0.82 | NPC1 (0.56) | NPC1RAB9ACASP3KMT2ASENP8 | |
| SCHEMBL29074222 | 0.82 | NSUN3 (0.56) | NSUN3KMT2AADORA3KDM4AKDM4B | |
| SCHEMBL29074244 | 0.82 | NSUN3 (0.56) | NPC1RAB9ANSUN3KMT2AADORA3 | |
| SCHEMBL29074202 | 0.81 | NPC1 (0.74) | NPC1RAB9ANSUN3KMT2AADORA3 | |
| SCHEMBL29074212 | 0.81 | NPC1 (0.76) | NPC1RAB9ANSUN3CASP3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116751195-B | Bipyridine compound, pharmaceutically acceptable salt thereof, preparation method and application | 杭州科兴生物化工有限公司 | 2025-03-07 | — | — | CN | disclosed |
| CN-116751195-A | Bipyridine compound, pharmaceutically acceptable salt thereof, preparation method and application | 杭州科兴生物化工有限公司 | 2023-09-15 | — | — | CN | disclosed |