Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 12/20 | 0.36 |
| ▸ | PPARA | Q07869 | 11/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8640704 | 0.72 | PPARG (0.41) | MTNR1AMTNR1BPPARGPPARAPOLB | |
| SCHEMBL9911413 | 0.72 | TSHR (0.41) | MTNR1AMTNR1BPPARGPPARAHPGD | |
| SCHEMBL13727892 | 0.67 | CYP19A1 (0.42) | ALOX15HPGD | |
| SCHEMBL7158598 | 0.66 | ALOX15 (0.63) | ALOX15HPGD | |
| SCHEMBL27476164 | 0.66 | TAAR1 (0.48) | HPGDTSHRPOLB | |
| SCHEMBL11279740 | 0.65 | SMN1; SMN2 (0.43) | MTNR1AMTNR1BPPARGPPARAALOX15 | |
| SCHEMBL4170593 | 0.65 | KMT2A (0.45) | MTNR1AMTNR1BPPARGPPARAALOX15 | |
| SCHEMBL28438685 | 0.65 | SLC1A3 (0.45) | MTNR1AMTNR1BPPARGPPARAHPGD | |
| SCHEMBL27783084 | 0.65 | CYP19A1 (0.44) | ALOX15HPGD | |
| SCHEMBL28206827 | 0.65 | CYP19A1 (0.44) | ALOX15HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112105624-B | Treatment of cancer using (2, 2-dihydroxymethyl) methylene cyclopropane nucleotides | 美迪维尔公司 | 2023-09-22 | — | — | CN | disclosed |