Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30061300 | 0.85 | ATM (0.57) | ATMALDH1A1KDM4EMMP13NPC1 | |
| SCHEMBL21053210 | 0.85 | ATM (0.57) | ATMALDH1A1KDM4EMMP13NPC1 | |
| SCHEMBL21053119 | 0.83 | ATM (0.47) | ATMALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL21091053 | 0.83 | RAB9A (0.44) | ATMALDH1A1KDM4EMMP13NPC1 | |
| SCHEMBL29074802 | 0.83 | NPC1 (0.54) | ATMALDH1A1KDM4EMMP13NPC1 | |
| SCHEMBL29074768 | 0.81 | MAPT (0.44) | ATMBRD4ALDH1A1KDM4EMMP13 | |
| SCHEMBL20779713 | 0.79 | TEAD1 (0.52) | ATMALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL25791128 | 0.78 | ATM (0.46) | ATMALDH1A1KDM4EMMP13NPC1 | |
| SCHEMBL21054113 | 0.77 | ATM (0.55) | ATMALDH1A1KDM4EMMP13NPC1 | |
| SCHEMBL30061310 | 0.77 | ATM (0.55) | ATMALDH1A1KDM4EMMP13NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116761795-A | Inhibitors of Transcription Enhancement Associated Domain (TEAD) and uses thereof | 达纳-法伯癌症研究所股份有限公司 | 2023-09-15 | — | — | CN | disclosed |