Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21091031 | 0.91 | MPO (0.43) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL21090690 | 0.90 | RAB9A (0.42) | RAB9ANPC1SMN1; SMN2MAPTTDP1 | |
| SCHEMBL29074802 | 0.89 | NPC1 (0.54) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL21053210 | 0.86 | ATM (0.57) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL30061300 | 0.86 | ATM (0.57) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL20552757 | 0.84 | HDAC6 (0.42) | MAPTALDH1A1HDAC6TP53LMNA | |
| SCHEMBL21053119 | 0.84 | ATM (0.47) | RAB9ANPC1SMN1; SMN2MAPTTDP1 | |
| SCHEMBL20779713 | 0.83 | TEAD1 (0.52) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL29074757 | 0.83 | ATM (0.43) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL25791128 | 0.78 | ATM (0.46) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019113236-A1 | BENZOCARBONYL COMPOUNDS | VIVACE THERAPEUTICS, INC. (US) | 2019-06-13 | — | — | WO | disclosed |