Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetone SCHEMBL7668393 | 0.92 | TSHR (0.48) | TSHRSLC1A3SLC1A2SLC1A1ALDH1A1 | |
| Acetic Acid Methyl Ester SCHEMBL3409715 | 0.87 | ALDH1A1 (0.50) | TSHRSLC1A3SLC1A2SLC1A1ALDH1A1 | |
| Butanone SCHEMBL3857935 | 0.87 | ALDH1A1 (0.50) | TSHRFFAR3SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL13611580 | 0.86 | — | — | |
| SCHEMBL16668528 | 0.86 | — | — | |
| SCHEMBL20648 | 0.86 | — | — | |
| Butanone SCHEMBL3678047 | 0.85 | ALDH1A1 (0.48) | TSHRALDH1A1TDP1MGAMGAA | |
| SCHEMBL5487434 | 0.83 | — | — | |
| Methyl Alcohol SCHEMBL14861497 | 0.83 | — | — | |
| Magnesium SCHEMBL31182158 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 527 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107428708-B | Benzoxazine low temperature curable compositions | 亨斯迈先进材料美国有限责任公司 | 2021-11-09 | — | — | CN | claimed |
| CN-110722623-B | Cutting protection structure | 拓旷(上海)光电科技有限公司 | 2021-07-27 | — | — | CN | claimed |
| CN-110903473-A | Preparation method of degradable hyperbranched dispersant | 苏州禾川化学技术服务有限公司 | 2020-03-24 | — | — | CN | claimed |
| CN-110722623-A | Cutting protection structure | 上海自旭光电科技有限公司 | 2020-01-24 | — | — | CN | claimed |
| CN-104272193-B | Diluent composition | 株式会社东进世美肯 | 2019-08-23 | — | — | CN | claimed |
| US-8975318-B2 | Halogen-free benzoxazine based curable compositions for high TG applications | HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) | 2015-03-10 | — | — | US | claimed |
| EP-2819642-A1 | PATTERNED NAIL VARNISH COMPOSITION | Fiabila (FR) | 2015-01-07 | — | — | EP | claimed |
| CN-104272193-A | diluent composition | DONGJIN SEMICHEM CO LTD | 2015-01-07 | — | — | CN | claimed |
| US-8912259-B2 | Formulated benzoxazine based system for transportation applications | HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) | 2014-12-16 | — | — | US | claimed |
| EP-2609136-B1 | FORMULATED BENZOXAZINE BASED SYSTEM FOR TRANSPORTATION APPLICATIONS | HUNTSMAN ADV MAT AMERICAS INC (US) | 2014-11-26 | — | — | EP | claimed |
| WO-2005062369-A1 | COMBINATIONS OF RESIN COMPOSITIONS AND METHODS OF USE THEREOF | GENERAL ELECTRIC COMPANY (US) | 2005-07-07 | — | — | WO | claimed |
| US-20050131106-A1 | Combinations of resin compositions and methods of use thereof | MOMENTIVE PERFORMANCE MATERIALS INC. | 2005-06-16 | — | — | US | claimed |
| WO-2005024938-A1 | SOLVENT-MODIFIED RESIN COMPOSITIONS AND METHODS OF USE THEREOF | GENERAL ELECTRIC COMPANY (US) | 2005-03-17 | — | — | WO | claimed |
| WO-2005024939-A1 | SOLVENT-MODIFIED RESIN SYSTEM CONTAINING FILLER THAT HAS HIGH Tg, TRANSPARENCY AND GOOD RELIABILITY IN WAFER LEVEL UNDERFILL APPLICATIONS | GENERAL ELECTRIC COMPANY (US) | 2005-03-17 | — | — | WO | claimed |
| US-20050049334-A1 | Solvent-modified resin system containing filler that has high Tg, transparency and good reliability in wafer level underfill applications | GENERAL ELECTRIC COMPANY | 2005-03-03 | — | — | US | claimed |
| US-20050049352-A1 | Solvent-modified resin compositions and methods of use thereof | GENERAL ELECTRIC COMPANY | 2005-03-03 | — | — | US | claimed |
| US-6605666-B1 | Stable alcohol and water dispersion of oligomeric polyactive hydrogen component, polyisocyanate and an ionic moiety; rapidly forms film when applied to skin; fluid resistance; strong adhesion | 3M INNOVATIVE PROPERTIES COMPANY | 2003-08-12 | — | — | US | claimed |
| EP-1309640-A1 | POLYURETHANE FILM-FORMING DISPERSIONS IN ALCOHOL-WATER SYSTEM | 3M Innovative Properties Company (US) | 2003-05-14 | — | — | EP | claimed |
| WO-2002010242-A1 | POLYURETHANE FILM-FORMING DISPERSIONS IN ALCOHOL-WATER SYSTEM | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2002-02-07 | — | — | WO | claimed |
| EP-0533159-A1 | Aqueous dispersions of fluorinated polyurethanes | SYREMONT S.p.A. (IT) | 1993-03-24 | — | — | EP | claimed |