Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17B | O94768 | 1/20 | 0.44 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.44 |
| ▸ | XPO1 | O14980 | 4/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 13/20 | 0.38 |
| ▸ | JUN | P05412 | 5/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 5/20 | 0.38 |
| ▸ | RELA | Q04206 | 5/20 | 0.38 |
| ▸ | ATF1 | P18846 | 9/20 | 0.37 |
| ▸ | JAK2 | O60674 | 2/20 | 0.36 |
| ▸ | JAK3 | P52333 | 2/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29076116 | 0.84 | ALDH1A1 (0.49) | STK17BSTK17ANFKB1JUNNFKB2 | |
| SCHEMBL5787248 | 0.81 | MAPK8 (0.43) | STK17BSTK17AXPO1NFKB1JUN | |
| SCHEMBL29076192 | 0.80 | XPO1 (0.42) | XPO1NFKB1JUNNFKB2RELA | |
| SCHEMBL13518478 | 0.80 | STK17B (0.41) | STK17BSTK17AXPO1NFKB1JUN | |
| SCHEMBL1568394 | 0.79 | HCAR3 (0.41) | STK17BSTK17AXPO1NFKB1JUN | |
| Fluoride SCHEMBL13517801 | 0.78 | STK17B (0.40) | STK17BSTK17AXPO1NFKB1JUN | |
| Fluoride SCHEMBL13518128 | 0.77 | HCAR3 (0.40) | STK17BSTK17AXPO1NFKB1JUN | |
| SCHEMBL22261174 | 0.77 | JAK3 (0.55) | STK17BSTK17AJAK2JAK3JAK1 | |
| SCHEMBL13518095 | 0.76 | STK17B (0.77) | STK17BSTK17ASIRT5 | |
| SCHEMBL7490862 | 0.75 | STK17B (0.48) | STK17BSTK17AXPO1NFKB1JUN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116514726-A | Pyrimidine derivative and application thereof | 四川大学 | 2023-08-01 | — | — | CN | disclosed |