Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.51 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.51 |
| ▸ | LIPE | Q05469 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29076463 | 0.95 | PKM (0.57) | EPHX2SCN9ALIPEPKMALDH1A1 | |
| SCHEMBL29076520 | 0.95 | PKM (0.58) | PKMSMN1; SMN2NPC1PKLRRAB9A | |
| SCHEMBL29076497 | 0.95 | PKM (0.57) | EPHX2SCN9ALIPEPKMALDH1A1 | |
| SCHEMBL29076514 | 0.94 | EPHX1 (0.57) | EPHX2MEN1KMT2AEPHX1HDAC3 | |
| SCHEMBL30586042 | 0.91 | SCN9A (0.47) | EPHX2MEN1KMT2AEPHX1HDAC3 | |
| SCHEMBL29076443 | 0.91 | SCN9A (0.47) | EPHX2MEN1KMT2AEPHX1HDAC3 | |
| SCHEMBL18702188 | 0.91 | EPHX2 (0.53) | EPHX2MEN1KMT2AEPHX1HDAC3 | |
| SCHEMBL18711920 | 0.87 | MEN1 (0.55) | EPHX2MEN1KMT2AEPHX1HDAC3 | |
| SCHEMBL29076540 | 0.86 | MEN1 (0.52) | MEN1KMT2ASCN9ASMN1; SMN2NPC1 | |
| SCHEMBL30586074 | 0.86 | MEN1 (0.52) | MEN1KMT2ASCN9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110372638-B | Piperazine AMPK agonist and medical application thereof | 中国药科大学 | 2023-09-22 | — | — | CN | disclosed |