Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | GPR183 | P32249 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30586074 | 1.00 | MEN1 (0.52) | MEN1KMT2ASCN9ARAB9AMAPT | |
| SCHEMBL29076419 | 0.90 | MEN1 (0.50) | MEN1KMT2ASCN9ARAB9AMAPT | |
| SCHEMBL30586077 | 0.90 | MEN1 (0.50) | MEN1KMT2ASCN9ARAB9AMAPT | |
| SCHEMBL29076463 | 0.87 | PKM (0.57) | SCN9AGPR183ALDH1A1L3MBTL1 | |
| SCHEMBL29076497 | 0.87 | PKM (0.57) | SCN9AGPR183ALDH1A1L3MBTL1 | |
| SCHEMBL29076533 | 0.86 | EPHX2 (0.52) | MEN1KMT2ASCN9ARAB9AALDH1A1 | |
| SCHEMBL30586042 | 0.83 | SCN9A (0.47) | MEN1KMT2ASCN9AMAPTALDH1A1 | |
| SCHEMBL29076443 | 0.83 | SCN9A (0.47) | MEN1KMT2ASCN9AMAPTALDH1A1 | |
| SCHEMBL18702068 | 0.83 | MEN1 (0.61) | MEN1KMT2ARAB9AGPR183USP2 | |
| SCHEMBL29076575 | 0.82 | SCN9A (0.49) | MEN1KMT2ASCN9AGPR183USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110372638-B | Piperazine AMPK agonist and medical application thereof | 中国药科大学 | 2023-09-22 | — | — | CN | disclosed |