Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.56 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.56 |
| ▸ | DHODH | Q02127 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.49 |
| ▸ | TOP1 | P11387 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | CKS1B | P61024 | 1/20 | 0.41 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | VHL | P40337 | 1/20 | 0.41 |
| ▸ | EDNRB | P24530 | 1/20 | 0.40 |
| ▸ | EDNRA | P25101 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30563610 | 0.98 | MKNK1 (0.58) | MKNK1MKNK2DHODHPTGS2PTGS1 | |
| SCHEMBL2084918 | 0.98 | MKNK1 (0.58) | MKNK1MKNK2DHODHPTGS2PTGS1 | |
| Hydrochloric Acid SCHEMBL1420842 | 0.96 | MKNK1 (0.56) | MKNK1MKNK2DHODHPTGS2PTGS1 | |
| SCHEMBL30022170 | 0.96 | MKNK1 (0.56) | MKNK1MKNK2DHODHPTGS2PTGS1 | |
| SCHEMBL15730173 | 0.94 | MKNK1 (0.59) | MKNK1MKNK2DHODHPTGS2PTGS1 | |
| SCHEMBL15730138 | 0.89 | MKNK1 (0.50) | MKNK1MKNK2DHODHPTGS2PTGS1 | |
| SCHEMBL16189062 | 0.87 | MKNK1 (0.57) | MKNK1MKNK2DHODHPTGS2PTGS1 | |
| SCHEMBL16189413 | 0.85 | MKNK1 (0.55) | MKNK1MKNK2DHODHPTGS2PTGS1 | |
| SCHEMBL30302892 | 0.83 | PTGS2 (0.46) | MKNK1MKNK2DHODHPTGS2PTGS1 | |
| SCHEMBL18104239 | 0.83 | MKNK1 (0.56) | MKNK1MKNK2DHODHPTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117946149-A | Beta-alkyl substituted silane compound, preparation method and application thereof | 武汉大学 | 2024-04-30 | — | — | CN | claimed |
| CN-116789693-A | Fluoroalkyl silicon-based diazonium compound, and preparation method and application thereof | 武汉大学 | 2023-09-22 | — | — | CN | claimed |
| CN-114456206-B | Alpha-fluoroalkyl substituted cyclopropylether/alcohol, preparation method and application thereof | 武汉大学 | 2023-09-12 | — | — | CN | claimed |
| CN-116854721-A | Difluoro cyclobutane, preparation method and application thereof | 武汉大学 | 2023-10-10 | — | — | CN | disclosed |
| CN-116789693-A | Fluoroalkyl silicon-based diazonium compound, and preparation method and application thereof | 武汉大学 | 2023-09-22 | — | — | CN | disclosed |