SCHEMBL18104239

SCHEMBL18104239

Cc1ncccc1-c1ccncc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MKNK1 Q9BUB5 1/20 0.56
MKNK2 Q9HBH9 1/20 0.56
DHODH Q02127 1/20 0.42
LMNA P02545 1/20 0.42
MAPT P10636 1/20 0.42
NOTUM Q6P988 1/20 0.41
PTGS2 P35354 3/20 0.40
PTGS1 P23219 2/20 0.40
PDE10A Q9Y233 2/20 0.40
NPC1 O15118 1/20 0.40
HSP90AA1 P07900 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
TDO2 P48775 2/20 0.39
PIK3CD O00329 1/20 0.39
MAPK14 Q16539 2/20 0.39
GCGR P47871 1/20 0.39
PRMT5 O14744 1/20 0.38
WDR77 Q9BQA1 1/20 0.38
IDO1 P14902 2/20 0.37
VHL P40337 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15161030 0.85 MKNK1 (0.48) MKNK1MKNK2DHODHNOTUMNPC1
SCHEMBL30563610 0.84 MKNK1 (0.58) MKNK1MKNK2DHODHPTGS2PTGS1
SCHEMBL2084918 0.84 MKNK1 (0.58) MKNK1MKNK2DHODHPTGS2PTGS1
Hydrochloric Acid SCHEMBL1420842 0.83 MKNK1 (0.56) MKNK1MKNK2DHODHPTGS2PTGS1
SCHEMBL30022170 0.83 MKNK1 (0.56) MKNK1MKNK2DHODHPTGS2PTGS1
SCHEMBL29077101 0.83 MKNK1 (0.56) MKNK1MKNK2DHODHPTGS2PTGS1
SCHEMBL7662428 0.83 MKNK1 (0.61) MKNK1MKNK2DHODHLMNAMAPT
SCHEMBL18174795 0.81 DHODH (0.46) MKNK1MKNK2DHODHMAPK14
SCHEMBL3421959 0.81 MKNK1 (0.52) MKNK1MKNK2LMNAMAPTPTGS2
SCHEMBL31469002 0.81 MKNK1 (0.52) MKNK1MKNK2LMNAMAPTPTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024059204-A1 HETEROARYL ANALOGS AS MGLU5 NEGATIVE ALLOSTERIC MODULATORS AND METHODS OF MAKING AND USING THE SAME VANDERBILT UNIVERSITY (US) 2024-03-21 WO disclosed
US-11818932-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-14 US disclosed
EP-3185330-B1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO LTD (KR) 2023-08-16 EP disclosed
US-11706973-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-18 US disclosed
US-11696496-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-04 US disclosed
US-11678498-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-13 US disclosed
US-11653563-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-16 US disclosed
US-11617290-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-03-28 US disclosed
US-11329230-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2022-05-10 US disclosed
US-11316117-B2 Organometallic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2022-04-26 US disclosed
US-20170117483-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-04-27 US disclosed
US-20170104166-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-04-13 US disclosed
US-20170069847-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME Research & Business Foundation Sungkyunkwan University (KR) 2017-03-09 US disclosed
US-20170069847-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME Research & Business Foundation Sungkyunkwan University (KR) 2017-03-09 US disclosed
US-20170054085-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-02-23 US disclosed
US-20170054085-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-02-23 US disclosed
US-20160322579-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-11-03 US disclosed
US-20160293845-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-10-06 US disclosed
US-20160293848-A1 CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2016-10-06 US disclosed
US-20160285011-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2016-09-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11329230-B2 Organic light-emitting device EML4, SUN2, TRPA1 MKNK1 3886/4885MKNK2 4096/4885DHODH 1447/4885
US-11706973-B2 Condensed cyclic compound and organic light-emitting device including the same C1S, CCNT1, C9 MKNK1 3981/4885MKNK2 4140/4885DHODH 4144/4885
US-20170104166-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNT1 MKNK1 2488/4885MKNK2 3222/4885DHODH 2619/4885
US-20160293848-A1 CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNE2 MKNK1 2383/4885MKNK2 3063/4885DHODH 2426/4885
US-20160285011-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING THE SAME CCNA1, CCNT1, CCNE2 MKNK1 3653/4885MKNK2 4083/4885DHODH 3330/4885
US-20170069847-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNE2 MKNK1 2615/4885MKNK2 3220/4885DHODH 1844/4885
US-11316117-B2 Organometallic compound and organic light-emitting device including the same OCIAD1, L3MBTL1, OCIAD2 MKNK1 2836/4885MKNK2 3533/4885DHODH 3442/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.