SCHEMBL29077232

SCHEMBL29077232

CC(=O)Nc1cc(N2C(=O)C3=C(CCCC3)C2=O)c(F)cc1Cl

nearest known ligand 0.78

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GRM7 Q14831 4/20 0.53
GRM4 Q14833 4/20 0.53
GRM1 Q13255 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29077264 0.85 GRM7 (0.49) GRM7GRM4GRM1
SCHEMBL29077298 0.85 GRM7 (0.49) GRM7GRM4GRM1
SCHEMBL29077241 0.85 GRM7 (0.49) GRM7GRM4GRM1
SCHEMBL29077234 0.85 GRM7 (0.52) GRM7GRM4GRM1
SCHEMBL29077255 0.84 GRM7 (0.51) GRM7GRM4GRM1
SCHEMBL29077260 0.83 GRM7 (0.50) GRM7GRM4GRM1
SCHEMBL29077273 0.83 GRM7 (0.50) GRM7GRM4GRM1
SCHEMBL29077292 0.82 GRM7 (0.49) GRM7GRM4GRM1
SCHEMBL10935535 0.81 GRM7 (0.48) GRM7GRM4GRM1
SCHEMBL29077230 0.80 GRM7 (0.45) GRM7GRM4GRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240300932-A1 N-PHENYLIMINE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF GUIZHOU UNIVERSITY (CN) 2024-09-12 US disclosed
WO-2024174317-A1 N-PHENYLIMINE-CONTAINING DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF 贵州大学 2024-08-29 WO disclosed
CN-116731003-A N-phenylimine-containing derivative, and preparation method and application thereof 贵州大学 2023-09-12 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240300932-A1 N-PHENYLIMINE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF PNMT, NNMT, PAH GRM7 1512/4885GRM4 1150/4885GRM1 684/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.