Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.81 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.81 |
| ▸ | TAS1R2 | Q8TE23 | 5/20 | 0.81 |
| ▸ | RAB9A | P51151 | 7/20 | 0.71 |
| ▸ | NPC1 | O15118 | 6/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | CASP3 | P42574 | 1/20 | 0.62 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.62 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.62 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL704779 | 0.90 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2RAB9ANPC1 | |
| SCHEMBL701923 | 0.88 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2RAB9ANPC1 | |
| SCHEMBL702041 | 0.87 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2RAB9ANPC1 | |
| SCHEMBL11143676 | 0.81 | TAS1R3 (0.73) | TAS1R3TAS1R1TAS1R2SMN1; SMN2POLB | |
| SCHEMBL997815 | 0.80 | KMT2A (0.74) | TAS1R3TAS1R1TAS1R2RAB9ANPC1 | |
| SCHEMBL14433857 | 0.80 | TAS1R3 (0.76) | TAS1R3TAS1R1TAS1R2RAB9ANPC1 | |
| SCHEMBL5923934 | 0.80 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2RAB9ANPC1 | |
| SCHEMBL10226339 | 0.79 | RAB9A (1.00) | TAS1R3TAS1R1TAS1R2RAB9ANPC1 | |
| SCHEMBL30515325 | 0.79 | RAB9A (1.00) | TAS1R3TAS1R1TAS1R2RAB9ANPC1 | |
| SCHEMBL25402971 | 0.77 | TAAR1 (0.70) | TAS1R3TAS1R1TAS1R2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116783190-A | N- (phenylaminocarbonyl) tetrahydroisoquinolines and related compounds as modulators of GPR65 | 帕蒂奥斯治疗有限公司 | 2023-09-19 | — | — | CN | disclosed |